Ríos-Chávez Patricia, Perez-Gonzalez Jordy, Salgado-Garciglia Rafael, Ramírez-Chávez Enrique, Molina-Torres Jorge, Martinez-Trujillo Miguel, Carreon-Abud Yazmin
Facultad de Biología, Universidad Michoacana de San Nicolás de Hidalgo, Cd. Universitaria, C.P 58030, Morelia, Michoacán, México.
Instituto Químico Biológico, Universidad Michoacana de San Nicolás de Hidalgo, Cd. Universitaria, C.P 58030, Morelia, Michoacán, México.
An Acad Bras Cienc. 2019 Jun 19;91(2):e20180468. doi: 10.1590/0001-3765201920180468.
This study evaluates the antibacterial, cytotoxic activities, and phytochemical composition, of Callistemon citrinus, Hibiscus rosa-sinensis and Plumbago auriculata leaves and flowers, three ornamental plants in Mexico. However, in other countries offers a range of other uses. Ethanol extracts of C. citrinus leaf and flower presented stronger antibacterial activity than the extracts obtained from the other two plants. C. citrinus leaf showed low cytotoxicity (LC50 <600 µg/mL) on the brine shrimp test, whereas the ethanol extracts of H. rosa-sinensis and P. auriculata leaves showed no cytotoxic activity. Flower extracts obtained from the three plants did no exhibit cytotoxicity. GC-MS analysis revealed that the ethanol extract of P. auriculata leaf contained lupeol triterpene and lupeol acetate, neither of them have been previously reported in this genus. Gamma sitosterol was present in the leaf and flower extracts of P. auriculata. Higher contents of linoleic and linolenic acids were found in extracts of H. rosa-sinensis leaves and flowers. The ability of the ethanol extracts of C. citrinus leaves and flowers to inhibit the growth of Gram-positive and Gram-negative bacteria indicates a potentially broad antimicrobial spectrum. Moreover, the absence of cytotoxicity suggests the potential use of this plant to treat microbial infections.
本研究评估了墨西哥三种观赏植物——柠檬桉、朱槿和耳状蓝雪花的叶子和花朵的抗菌、细胞毒性活性以及植物化学成分。然而，在其他国家，它们还有一系列其他用途。柠檬桉叶和花的乙醇提取物比从其他两种植物中获得的提取物具有更强的抗菌活性。在卤虫试验中，柠檬桉叶表现出低细胞毒性（LC50<600µg/mL），而朱槿叶和耳状蓝雪花叶的乙醇提取物未表现出细胞毒性活性。从这三种植物中获得的花提取物未表现出细胞毒性。气相色谱-质谱分析表明，耳状蓝雪花叶的乙醇提取物含有羽扇豆醇三萜和乙酸羽扇豆醇，此前在该属中均未报道过。γ-谷甾醇存在于耳状蓝雪花的叶和花提取物中。朱槿叶和花的提取物中发现了较高含量的亚油酸和亚麻酸。柠檬桉叶和花的乙醇提取物抑制革兰氏阳性菌和革兰氏阴性菌生长的能力表明其具有潜在的广泛抗菌谱。此外，无细胞毒性表明该植物在治疗微生物感染方面具有潜在用途。
