恰加斯病：有症状和无症状患者对克氏锥虫亚细胞组分的体液反应。
Chagas' disease: humoral response to subcellular fraction of Trypanosoma cruzi in symptomatic and asymptomatic patients.
作者信息
de Titto E H, Moreno M, Braun M, Segura E L
机构信息
Instituto Nacional de Diagnóstico e Investigación de la Enfermedad de Chagas, Buenos Aires, Argentina.
出版信息
Trop Med Parasitol. 1987 Sep;38(3):163-6.
PMID:3124252
Abstract
The capacity of antibodies in serum from individuals with chronic Chagas' disease to react with antigens in different subcellular fractions of Trypanosoma cruzi varied according to the clinical status of the patients. Antibodies in serum of asymptomatic patients were directed mostly against antigens in the citosol of the parasite, whereas in overtly cardiopathic patients antibodies were directed mostly against antigens in the microsomal fractions.
摘要
慢性恰加斯病患者血清中的抗体与克氏锥虫不同亚细胞组分中的抗原发生反应的能力，因患者的临床状况而异。无症状患者血清中的抗体主要针对寄生虫胞质溶胶中的抗原，而明显患有心脏病的患者血清中的抗体主要针对微粒体组分中的抗原。
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