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吲哚菁绿在小儿外科中的应用。

Application of indocyanine green in pediatric surgery.

作者信息

Lau C T, Au D M, Wong K K Y

机构信息

Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Pokfulam Road, Hong Kong SAR, China.

出版信息

Pediatr Surg Int. 2019 Oct;35(10):1035-1041. doi: 10.1007/s00383-019-04502-4. Epub 2019 Jun 26.

DOI:10.1007/s00383-019-04502-4
PMID:31243546
Abstract

The use of near-infrared (NIR) fluorescence imaging with indocyanine green (ICG) has gained popularity in many fields in adult surgery, such as sentinel lymph node mapping, intra-operative solid tumor identification, and organ perfusion assessment. However, the clinical application of ICG in pediatric surgery is just at the beginning. This review paper presents the advantages, current applications and potential developments of NIR fluorescence imaging with ICG in our field.

摘要

使用吲哚菁绿(ICG)的近红外(NIR)荧光成像在成人外科的许多领域已得到广泛应用,如前哨淋巴结 mapping、术中实体瘤识别和器官灌注评估。然而,ICG在小儿外科的临床应用才刚刚起步。本文综述了ICG近红外荧光成像在我们领域的优势、当前应用和潜在发展。

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Application of indocyanine green in pediatric surgery.吲哚菁绿在小儿外科中的应用。
Pediatr Surg Int. 2019 Oct;35(10):1035-1041. doi: 10.1007/s00383-019-04502-4. Epub 2019 Jun 26.
2
Clinical application and technical standardization of indocyanine green (ICG) fluorescence imaging in pediatric minimally invasive surgery.吲哚菁绿(ICG)荧光成像在小儿微创手术中的临床应用与技术标准化
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Dis Colon Rectum. 2019 Nov;62(11):1401. doi: 10.1097/DCR.0000000000001475.
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Indocyanine green near infrared-guided surgery in children, adolescents, and young adults with otolaryngologic malignancies.吲哚菁绿近红外光引导手术在儿童、青少年和青年期头颈部恶性肿瘤患者中的应用。
Auris Nasus Larynx. 2023 Aug;50(4):576-585. doi: 10.1016/j.anl.2022.11.007. Epub 2022 Dec 8.
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The identification of sub-centimetre nodules by near-infrared fluorescence thoracoscopic systems in pulmonary resection surgeries.近红外荧光胸腔镜系统在肺切除术中对亚厘米结节的识别。
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Breast cancer sentinel lymph node mapping using near infrared guided indocyanine green and indocyanine green--human serum albumin in comparison with gamma emitting radioactive colloid tracer.近红外荧光吲哚菁绿和吲哚菁绿-人血清白蛋白联合放射性胶体示踪剂在乳腺癌前哨淋巴结定位中的应用比较
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Advances in Fluorescent Adjuncts in Pediatric Surgery: A Comprehensive Review of Applications of Indocyanine Green Across Surgical Specialties.小儿外科荧光辅助技术的进展:吲哚菁绿在各外科专业应用的全面综述
Children (Basel). 2025 Aug 9;12(8):1048. doi: 10.3390/children12081048.
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Indocyanine Green Fluorescence Navigation in Pediatric Hepatobiliary Surgery: Systematic Review.小儿肝胆外科中的吲哚菁绿荧光导航:系统评价
Children (Basel). 2025 Jul 18;12(7):950. doi: 10.3390/children12070950.
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Photodynamic therapy could serve as a promising approach to prevent posterior capsular opacification.

本文引用的文献

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Navigation surgery using indocyanine green fluorescent imaging for hepatoblastoma patients.使用吲哚菁绿荧光成像技术对肝母细胞瘤患者进行导航手术。
Pediatr Surg Int. 2019 May;35(5):551-557. doi: 10.1007/s00383-019-04458-5. Epub 2019 Feb 16.
2
Indocyanine Green Fluorescence Lymphography: A New Technique to Perform Lymphatic Sparing Laparoscopic Palomo Varicocelectomy in Children.吲哚菁绿荧光淋巴造影术:一种在儿童中进行保留淋巴管的腹腔镜Palomo精索静脉曲张切除术的新技术。
J Laparoendosc Adv Surg Tech A. 2019 Apr;29(4):564-567. doi: 10.1089/lap.2018.0624. Epub 2019 Jan 24.
3
Pure laparoscopic hepatectomy with augmented reality-assisted indocyanine green fluorescence versus open hepatectomy for hepatocellular carcinoma with liver cirrhosis: A propensity analysis at a single center.
光动力疗法可能是预防后囊膜混浊的一种有前景的方法。
Photochem Photobiol Sci. 2025 May;24(5):681-691. doi: 10.1007/s43630-025-00707-w. Epub 2025 May 7.
4
Practical Guidelines for the Use of Indocyanine Green in Different Branches of Pediatric Surgery: A Polish Nationwide Multi-Center Retrospective Cohort Study.小儿外科不同分支中吲哚菁绿使用的实用指南:一项波兰全国多中心回顾性队列研究
Health Sci Rep. 2025 Mar 23;8(3):e70586. doi: 10.1002/hsr2.70586. eCollection 2025 Mar.
5
Cerebral Aneurysms and Arteriovenous Malformation: Preliminary Experience with the Use of Near-Infrared Fluorescence Imaging Applied to Endoscopy.脑动脉瘤和动静脉畸形:近红外荧光成像应用于内镜检查的初步经验
J Pers Med. 2024 Nov 22;14(12):1117. doi: 10.3390/jpm14121117.
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Synthesis, Characterization, and Potential Usefulness in Liver Function Assessment of Novel Bile Acid Derivatives with Near-Infrared Fluorescence (NIRBAD).新型近红外荧光胆汁酸衍生物(NIRBAD)的合成、表征及其在肝功能评估中的潜在应用价值
Bioconjug Chem. 2024 Jul 17;35(7):971-980. doi: 10.1021/acs.bioconjchem.4c00168. Epub 2024 Jul 3.
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J Mater Sci Mater Med. 2024 Jun 19;35(1):32. doi: 10.1007/s10856-024-06802-1.
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European J Pediatr Surg Rep. 2023 Jun 12;11(1):e32-e35. doi: 10.1055/s-0043-1769106. eCollection 2023 Jan.
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Nat Commun. 2023 May 16;14(1):2241. doi: 10.1038/s41467-023-37714-3.
纯腹腔镜肝切除术联合增强现实辅助吲哚菁绿荧光与开腹肝切除术治疗肝硬化肝细胞癌:单中心倾向分析
Asian J Endosc Surg. 2018 May;11(2):104-111. doi: 10.1111/ases.12492. Epub 2018 May 10.
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J Thorac Cardiovasc Surg. 2017 Aug;154(2):702-711. doi: 10.1016/j.jtcvs.2017.03.140. Epub 2017 Apr 13.
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