Department of Kinesiology, University of Waterloo, 200 University Avenue West, Waterloo, ON, N2L 3G1, Canada.
University of Western Ontario, London, ON, Canada.
Arch Osteoporos. 2019 Jun 26;14(1):67. doi: 10.1007/s11657-019-0626-x.
The main objective of this study was to explore whether vertebral fracture characteristics or posture is independently associated with physical performance. Posture was significantly associated with physical performance but fracture characteristics were not, suggesting posture should be the focus of physical performance variance.
The main objective of this study was to explore whether vertebral fracture characteristics (number, severity, location) or occiput-to-wall distance (OWD) is independently associated with physical performance.
This was a secondary data analysis using baseline data from a randomized controlled trial, of community-dwelling women aged 65 years and older with a suspected vertebral fragility fracture. Lateral thoracic and lumbar spine radiographs were used to determine the number, location, and severity of fracture. The dependent variables were timed up and go (TUG), five times sit-to-stand, four-meter walk, and step test. The independent variables were number, severity, location of fracture, and OWD. Pain during movement and age were covariates. Multivariable regression analyses determined the association between each of the dependent and independent variables.
Participants' (n = 158) mean (standard deviation [SD]) age was 75.9 (6.5) years. They had a mean (SD) BMI, OWD, and number of fractures of 26.7 (5.3) kg/m, 5.7 (4.6) cm, and 2.2 (1.8), respectively. OWD was independently associated with TUG (estimated coefficient [B] = 0.29, 95% confidence interval [CI] = 0.16, 0.42), five times sit-to-stand (B = 0.33, 95% CI = 0.12, 0.55), four-meter walk (B = 0.09, 95% CI = 0.05, 0.13), and step test (B = - 0.36, 95% CI = - 0.50, - 0.23) in the unadjusted model. OWD was independently associated with TUG (B = 0.25, 95% CI = 0.12, 0.38), five times sit-to-stand (B = 0.29, 95% CI = 0.07, 0.50), four-meter walk (B = 0.08, 95% CI = 0.03, 0.12), and step test (B = - 0.22, 95% CI = - 0.47, - 0.19) in the adjusted model.
OWD was significantly associated with physical performance but fracture characteristics were not. These analyses were exploratory and require replication in future studies.
本研究的主要目的是探讨椎体骨折特征（数量、严重程度、部位）或枕骨到墙距离（OWD）是否与身体表现独立相关。
这是一项使用社区居住的年龄在 65 岁及以上、疑似脆性椎体骨折的女性随机对照试验的基线数据进行的二次数据分析。使用侧位胸腰椎 X 光片确定骨折的数量、部位和严重程度。因变量是计时起立行走（TUG）、五次坐站、四米步行和台阶测试。自变量是数量、严重程度、骨折部位和 OWD。运动时的疼痛和年龄是协变量。多变量回归分析确定了每个因变量和自变量之间的关联。
参与者（n=158）的平均（标准差[SD]）年龄为 75.9（6.5）岁。他们的平均（SD）体重指数、OWD 和骨折数量分别为 26.7（5.3）kg/m、5.7（4.6）cm 和 2.2（1.8）。OWD 与 TUG（估计系数[B]为 0.29，95%置信区间[CI]为 0.16，0.42）、五次坐站（B=0.33，95%CI 为 0.12，0.55）、四米步行（B=0.09，95%CI 为 0.05，0.13）和台阶测试（B=-0.36，95%CI 为-0.50，-0.23）独立相关，在未调整模型中。OWD 与 TUG（B=0.25，95%CI 为 0.12，0.38）、五次坐站（B=0.29，95%CI 为 0.07，0.50）、四米步行（B=0.08，95%CI 为 0.03，0.12）和台阶测试（B=-0.22，95%CI 为-0.47，-0.19）独立相关，在调整后的模型中。
OWD 与身体表现显著相关，但骨折特征无关。这些分析是探索性的，需要在未来的研究中复制。
