单克隆丙种球蛋白病中的免疫调节和分化标志物

Immunoregulation and differentiation markers in monoclonal gammopathies.

作者信息

Ricci C, Cascio G, Canavera R, Basso M, Baldassi R

机构信息

Institute of Internal Medicine, University Hospital, Torino, Italy.

出版信息

Acta Haematol. 1987;78 Suppl 1:50-5. doi: 10.1159/000205903.

DOI:10.1159/000205903

PMID:3124450

Abstract

Multiple myeloma and benign monoclonal gammopathies (BMG) are regarded as monoclonal B cell proliferations in which B lymphocyte maturation is blocked in the final stages of the differentiation cycle. Further studies with monoclonal antibodies (MoAbs) of the FMC series and of the 791T/36 MoAb will perhaps provide a final subclassification of the B lymphocyte proliferation diseases and hopefully assist in their diagnosis and treatment.

摘要

多发性骨髓瘤和良性单克隆丙种球蛋白病（BMG）被视为单克隆B细胞增殖性疾病，其中B淋巴细胞成熟在分化周期的最后阶段受阻。使用FMC系列单克隆抗体（MoAb）和791T/36 MoAb进行的进一步研究可能会为B淋巴细胞增殖性疾病提供最终的亚分类，并有望有助于其诊断和治疗。