Szepesházi K, Lapis K
1st Institute of Pathology and Experimental Cancer Research, Semmelweis Medical University Budapest, Hungary.
Acta Morphol Hung. 1987;35(1-2):77-88.
Rhizoplast or striated rootlet is a rarely described cytoplasmic organelle in non-ciliated mammalian cells. We observed the centrosome related rhizoplast like structures relatively often in the human renal glomerular cells. Of 226 kidney biopsies striated microfilament bundles (SMF) have been found in 41 cases in a total of 64 cells. More than half of these organelles were found in podocytes, about a quarter in endothelial cells, fewer in mesangial cells and they rarely occurred in the parietal epithelium. The majority of SMF are connected with the centrosome, but not in direct connection with the centriole. The longer bundles have often been located near the Golgi complex. The thickness of the SMF varies, their cross striation has a periodicity of 88 +/- 13.4 nm. The occurrence of SMF does not show any connection with the age of the patients, the type of disease, the morphological changes or therapy. It is difficult to say whether they are normal or pathological organelles. Their presence can be regarded as a metaplastic process in functionally overloaded cells.
根丝体或横纹小根是一种在无纤毛哺乳动物细胞中很少被描述的细胞质细胞器。我们在人肾小球细胞中相对频繁地观察到与中心体相关的类根丝体结构。在226例肾活检中，共在64个细胞的41例中发现了横纹微丝束（SMF）。这些细胞器一半以上存在于足细胞中，约四分之一存在于内皮细胞中，系膜细胞中较少，在壁层上皮细胞中很少出现。大多数SMF与中心体相连，但与中心粒无直接联系。较长的微丝束常位于高尔基体附近。SMF的厚度各不相同，其横纹周期为88±13.4纳米。SMF的出现与患者年龄、疾病类型、形态学改变或治疗均无关联。很难说它们是正常细胞器还是病理性细胞器。它们的存在可被视为功能过载细胞中的一种化生过程。
