Suppr超能文献

利用诱导多能干细胞治疗脊髓损伤

Cell therapy for spinal cord injury using induced pluripotent stem cells.

作者信息

Nagoshi Narihito, Tsuji Osahiko, Nakamura Masaya, Okano Hideyuki

机构信息

Department of Orthopaedic Surgery, Keio University School of Medicine, Japan.

Department of Physiology, Keio University School of Medicine, Japan.

出版信息

Regen Ther. 2019 Jun 13;11:75-80. doi: 10.1016/j.reth.2019.05.006. eCollection 2019 Dec.

Abstract

For the past few decades, spinal cord injury (SCI) has been believed to be an incurable traumatic condition, but with recent developments in stem cell biology, the field of regenerative medicine has gained hopeful momentum in the development of a treatment for this challenging pathology. Among the treatment candidates, transplantation of neural precursor cells has gained remarkable attention as a reasonable therapeutic intervention to replace the damaged central nervous system cells and promote functional recovery. Here, we highlight transplantation therapy techniques using induced pluripotent stem cells to treat SCI and review the recent research giving consideration to future clinical applications.

摘要

在过去几十年里,脊髓损伤(SCI)一直被认为是一种无法治愈的创伤性疾病,但随着干细胞生物学的最新发展,再生医学领域在开发针对这一具有挑战性病理状况的治疗方法方面获得了充满希望的动力。在候选治疗方法中,神经前体细胞移植作为一种合理的治疗干预手段,用以替代受损的中枢神经系统细胞并促进功能恢复,已受到显著关注。在此,我们重点介绍使用诱导多能干细胞治疗脊髓损伤的移植治疗技术,并回顾近期的研究,同时考虑未来的临床应用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fb53/6581851/5bccbadf5b37/gr1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验