a Department of Psychological Medicine, Section of Eating Disorders , Institute of Psychiatry, Psychology, & Neuroscience (IoPPN), King's College London , London , UK.
b Forensic and Neurodevelopmental Sciences, Institute of Psychiatry, Psychology, & Neuroscience (IoPPN) , King's College London , London , UK.
Int Rev Psychiatry. 2019 Jun;31(4):318-331. doi: 10.1080/09540261.2019.1622515. Epub 2019 Jun 27.
A systematic review was conducted to investigate event-related potentials (ERPs) in response to food and non-food stimuli among individuals with eating and weight disorders. Limiting the search to studies that have analysed ERPs relating to motivated attention and inhibitory control, 19 research papers were extracted from a systematic search in PubMed, Ovid, and Web of Science (2000-2018). An enhanced attentional bias towards food over non-food images (as indexed by P3(00) and LPP amplitudes) was evident for all populations. Individuals with binge eating disorder showed an enhanced attentional response to food cues compared to healthy controls. Inhibitory control-related ERP components (N2(00) and P3a) increased during food-specific no-go trials, but did not differentiate overweight from 'healthy' weight groups. The N2 amplitude to food pictures were positively correlated with caloric intake and food craving among individuals with obesity and binge eating disorder, respectively, while P3(00) was sensitive to hunger levels among overweight and obese females. The heterogeneity of stimuli/paradigms adopted, component timescales extracted, ERPs analysed, and data presented has challenged this review's ability to produce a robust synthesis of results. Some recommendations for future research are discussed.
一项系统评价旨在调查饮食和体重障碍个体对食物和非食物刺激的事件相关电位（ERPs）。本研究限制在分析与动机注意和抑制控制相关的 ERPs 的研究中，从 PubMed、Ovid 和 Web of Science（2000-2018 年）进行系统检索中提取了 19 篇研究论文。所有人群均表现出对食物图像的注意力增强偏向（以 P3(00)和 LPP 幅度为指标），而对非食物图像的注意力偏向减弱。与健康对照组相比，暴食障碍个体对食物线索表现出增强的注意力反应。在特定于食物的不能反应试验中，与抑制控制相关的 ERP 成分（N2(00)和 P3a）增加，但不能区分超重与“健康”体重组。肥胖和暴食障碍个体的食物图片 N2 振幅与热量摄入和食物渴望呈正相关，而 P3(00)对超重和肥胖女性的饥饿水平敏感。所采用的刺激/范式、提取的成分时程、分析的 ERPs 和呈现的数据的异质性，挑战了本综述产生稳健结果综合的能力。讨论了一些对未来研究的建议。
