Finn Abigail E, Baldwin Alex S, Reynaud Alexandre, Hess Robert F
McGill Vision Research, Department of Ophthalmology & Visual Sciences, McGill University, Montreal, Quebec, Canada.
J Vis. 2019 Jun 3;19(6):21. doi: 10.1167/19.6.21.
Experiments using enriched environments have shown that physical exercise modulates visual plasticity in rodents. A recent study (Lunghi & Sale, 2015) investigated whether exercise also affects visual plasticity in adult humans. The plastic effect they measured was the shift in ocular dominance caused by 2 hr of monocular deprivation (e.g., by an eye patch). They used a binocular rivalry task to measure this shift. They found that the magnitude of the shift was increased by exercise during the deprivation period. This effect of exercise was later disputed by a study that used a different behavioral task (Zhou, Reynaud, & Hess, 2017). Our goal was to determine whether the difference in task was responsible for that study's failure to find an exercise effect. We set out to replicate Lunghi and Sale (2015). We measured ocular dominance with a rivalry task before and after 2 hr of deprivation. We measured data from two conditions in 30 subjects. On two separate days, they either performed exercise or rested during the deprivation period. Contrary to the previous study, we find no significant effect of exercise. We hypothesize that exercise may affect rivalry dynamics in a way that interacts with the measurement of the deprivation effect.
使用丰富环境的实验表明，体育锻炼可调节啮齿动物的视觉可塑性。最近一项研究（Lunghi和Sale，2015年）调查了锻炼是否也会影响成年人类的视觉可塑性。他们测量的可塑性效应是由2小时单眼剥夺（例如，通过眼罩）引起的眼优势转移。他们使用双眼竞争任务来测量这种转移。他们发现，在剥夺期进行锻炼会增加转移的幅度。后来，一项使用不同行为任务的研究（Zhou、Reynaud和Hess，2017年）对锻炼的这种效果提出了质疑。我们的目标是确定任务差异是否是该研究未能发现锻炼效果的原因。我们着手重复Lunghi和Sale（2015年）的研究。我们在2小时剥夺前后使用竞争任务测量眼优势。我们测量了30名受试者在两种条件下的数据。在两个不同的日子里，他们在剥夺期要么进行锻炼，要么休息。与之前的研究相反，我们没有发现锻炼的显著效果。我们假设锻炼可能以一种与剥夺效应测量相互作用的方式影响竞争动态。
