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认知康复和暴露/分类治疗对老年囤积症的影响:对神经心理学表现的影响。

Cognitive Rehabilitation and Exposure/Sorting Therapy for Late-Life Hoarding: Effects on Neuropsychological Performance.

机构信息

Mental Healthcare Line, VA San Diego Healthcare System, California.

Department of Psychiatry, University of California, San Diego School of Medicine, La Jolla.

出版信息

J Gerontol B Psychol Sci Soc Sci. 2020 Jun 2;75(6):1193-1198. doi: 10.1093/geronb/gbz062.

Abstract

OBJECTIVES

Hoarding disorder (HD) is characterized by urges to save items, difficulty discarding possessions, and excessive clutter and has been associated with executive functioning deficits. A randomized controlled trial comparing Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST) with a care management control condition demonstrated the efficacy of CREST in reducing hoarding symptoms in older adults. The purpose of the current study was to assess whether CREST may also lead to improved executive functioning.

METHOD

All participants were administered a neurocognitive battery at baseline and posttreatment. Linear mixed models with random intercepts were used to evaluate change in global neuropsychological functioning as well as change in individual executive functioning variables.

RESULTS

There was no significant group by time interaction for the Global Deficit score; however, there were significant group by time interactions on two of the executive functioning variables examined, such that participants in the CREST condition demonstrated significant improvement in cognitive flexibility and inhibition over time compared with the participants in the care management condition.

DISCUSSION

Our initial findings support the notion that CREST may be able to improve task switching, an important component of executive functioning, in older adults with HD.

摘要

目的

囤积症(HD)的特点是有保存物品的冲动、难以丢弃物品,以及过度杂乱,并且与执行功能缺陷有关。一项比较认知康复和暴露/分类治疗(CREST)与护理管理对照条件的随机对照试验表明,CREST 可有效减少老年人的囤积症状。本研究的目的是评估 CREST 是否也可以改善执行功能。

方法

所有参与者在基线和治疗后均接受神经认知测试。采用随机截距线性混合模型评估整体神经心理功能的变化以及个体执行功能变量的变化。

结果

全球缺陷评分的组间时间交互作用不显著;然而,在两个被检查的执行功能变量上存在显著的组间时间交互作用,即与护理管理组相比,CREST 组的认知灵活性和抑制能力随时间显著提高。

讨论

我们的初步发现支持了 CREST 可能能够改善执行功能中重要组成部分——任务转换的观点,在患有 HD 的老年人中。

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