将决定人类碳酸酐酶CAI的基因定位于8号染色体。
Assignment of the gene determining human carbonic anhydrase, CAI, to chromosome 8.
作者信息
Edwards Y H, Barlow J H, Konialis C P, Povey S, Butterworth P H
机构信息
M.R.C. Human Biochemical Genetics Unit, Galton Laboratory, University College London.
出版信息
Ann Hum Genet. 1986 May;50(2):123-9. doi: 10.1111/j.1469-1809.1986.tb01030.x.
A cDNA clone complementary to the mRNA encoding the rabbit erythrocyte specific carbonic anhydrase, CAI, has been used as probe for human CAI sequences in the analysis of DNA from panels of rodent/human somatic cell hybrids. The presence of the human CAI gene in all hybrids correlates with the presence of chromosome 8. Together with published mapping data, this assignment indicates that three CA loci are situated on chromosome 8.
一个与编码兔红细胞特异性碳酸酐酶CAI的mRNA互补的cDNA克隆，已被用作分析啮齿动物/人类体细胞杂种DNA中人类CAI序列的探针。在所有杂种中人类CAI基因的存在与8号染色体的存在相关。结合已发表的定位数据，这一归属表明三个CA基因座位于8号染色体上。
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