Bergenhem N C, Sait S S, Eddy R L, Shows T B, Tashian R E
Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109-0618, USA.
Cytogenet Cell Genet. 1995;71(3):299-300. doi: 10.1159/000134131.
The human carbonic anhydrase (CA) VIII gene (CA8) has been mapped to chromosome 8 at q11-->q12 by human-mouse hybrid mapping and by fluorescence in situ hybridization. The closely-linked human CA isozyme genes, CA1, CA2 and CA3, are also located on chromosome 8, but at q22, and therefore not closely linked to the CA8 locus.
人类碳酸酐酶(CA)VIII基因(CA8)已通过人鼠杂交定位和荧光原位杂交定位到8号染色体的q11→q12区域。紧密连锁的人类CA同工酶基因CA1、CA2和CA3也位于8号染色体上,但在q22位置,因此与CA8基因座没有紧密连锁。