Zannoli Silvia, Sambri Vittorio
Unit of Microbiology, The Great Romagna Area Hub Laboratory, Pievesestina, 47522 Cesena, Italy.
Department of Experimental, Diagnostic and Specialty Medicine (DIMES), University of Bologna, 40138 Bologna, Italy.
Microorganisms. 2019 Jun 26;7(7):184. doi: 10.3390/microorganisms7070184.
West Nile virus (WNV) and Usutu virus (USUV) are neurotropic mosquito-borne flaviviruses that may infect humans. Although WNV is much more widespread and plays a much larger role in human health, the two viruses are characterized by similar envelope antigens, clinical manifestations, and present overlapping in terms of geographic range of transmission, host, and vector species. This review highlights some of the most relevant aspects of WNV and USUV human infections in Europe, and the possible implications of their co-circulation.
西尼罗河病毒(WNV)和乌苏图病毒(USUV)是嗜神经性蚊媒黄病毒,可感染人类。尽管西尼罗河病毒分布更为广泛,且在人类健康方面发挥着更大作用,但这两种病毒具有相似的包膜抗原、临床表现,并且在传播地理范围、宿主和媒介物种方面存在重叠。本综述重点介绍了欧洲西尼罗河病毒和乌苏图病毒人类感染的一些最相关方面,以及它们共同传播可能产生的影响。