Andrew P W, Robertson A K, Lowrie D B, Cross A R, Jones O T
Department of Microbiology, University of Leicester, U.K.
Biochem J. 1987 Nov 15;248(1):281-3. doi: 10.1042/bj2480281.
Increased amounts of cytochrome b-245 and a 45 kDa polypeptide component of the hydrogen peroxide-generating oxidase were detected in the human monocytic cell line U937 after incubation in interferon-gamma. The time course of increase in cytochrome b-245 paralleled the induction of oxidase activity. Induction of the 45 kDa component had a different time course, having a greater lag before increased amounts were seen.
在人单核细胞系U937中,经γ干扰素孵育后,检测到过氧化氢生成氧化酶的细胞色素b - 245和一种45 kDa多肽成分的量增加。细胞色素b - 245增加的时间进程与氧化酶活性的诱导平行。45 kDa成分的诱导具有不同的时间进程,在其含量增加之前有更长的延迟。