Department of Urology, Seoul National University Bundang Hospital, Seongnam 13620, Korea.
Department of Urology, Catholic Kwandong Univerisity International St. Mary's Hospital, Incheon 22711, Korea.
Asian J Androl. 2020 May-Jun;22(3):280-286. doi: 10.4103/aja.aja_62_19.
We evaluated contemporary trends in radical prostatectomy (RP) in men aged >70 years and investigated associations of selected variables with recovery of urinary continence (UC) in two age groups: >70 and ≤ 70 years. A retrospective cohort of 2301 eligible patients attending our institution from 2004 to 2015 was reviewed. Patients were divided into two groups based on age at surgery (>70 years [n = 610] vs 70 years [n = 1691]) and four groups by year of surgery. Over the study period, the proportion of patients aged >70 years gradually increased up to 30.0%, and the rate of robot-assisted RP and neurovascular bundle (NVB) saving increased continually to 80.0% and 67.4% of older patients, respectively. Although the rate of recovery of UC within 12 months (3 months) in patients aged >70 years was lower than that in those aged ≤ 70 years (81.5% [52.6%] vs 88.6% [60.9%], respectively; both P < 0.001), the gap between age groups in the rate of recovery within 12 months narrowed from the second quarter of the study period. Among younger patients, age, robot-assisted RP, prostate volume, membranous urethral length (MUL), and NVB saving were predictors of recovery of UC within 3 or 12 months. In contrast, only age and MUL were predictors of recovery of UC within 3 and 12 months in patients aged >70 years. Therefore, unlike younger patients, only variables (age and MUL), possibly associated with the inherent function of the urinary sphincter, were predictors of recovery of UC in patients aged >70 years.
我们评估了>70 岁男性接受根治性前列腺切除术(RP)的当代趋势,并研究了两个年龄组(>70 岁和≤70 岁)中选定变量与尿控(UC)恢复之间的关联。我们回顾了 2004 年至 2015 年在我们机构就诊的 2301 名符合条件的患者的回顾性队列。根据手术时的年龄(>70 岁[610 例]与 70 岁[1691 例])将患者分为两组,并按手术年份分为四组。在研究期间,>70 岁患者的比例逐渐增加至 30.0%,机器人辅助 RP 和神经血管束(NVB)保存的比例分别持续增加至 80.0%和 67.4%。尽管>70 岁患者术后 12 个月(3 个月)UC 恢复率低于≤70 岁患者(分别为 81.5%[52.6%]和 88.6%[60.9%];均<0.001),但两组间 12 个月内 UC 恢复率的差距在研究期间的第二个季度缩小。在年轻患者中,年龄、机器人辅助 RP、前列腺体积、膜状尿道长度(MUL)和 NVB 保存是术后 3 个月或 12 个月 UC 恢复的预测因素。相比之下,只有年龄和 MUL 是>70 岁患者术后 3 个月和 12 个月 UC 恢复的预测因素。因此,与年轻患者不同,只有可能与尿括约肌固有功能相关的变量(年龄和 MUL)是>70 岁患者 UC 恢复的预测因素。