Pachón Vanessa, Trujillo-Santos Javier, Domènech Pere, Gallardo Enrique, Font Carmen, González-Porras José Ramón, Pérez-Segura Pedro, Maestre Ana, Mateo José, Muñoz Andrés, Peris María Luisa, Lecumberri Ramón
Department of Oncology, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Department of Internal Medicine, Hospital Universitario Santa Lucía, Cartagena, Spain.
TH Open. 2018 Nov 5;2(4):e373-e386. doi: 10.1055/s-0038-1675577. eCollection 2018 Oct.
Despite the growing interest and improved knowledge about venous thromboembolism in cancer patients in the last years, there are still many unsolved issues. Due to the limitations of the available literature, evidence-based clinical practice guidelines are not able to give solid recommendations for challenging scenarios often present in the setting of cancer-associated thrombosis (CAT). A multidisciplinary expert panel from three scientific societies-Spanish Society of Internal Medicine (SEMI), Spanish Society of Medical Oncology (SEOM), and Spanish Society Thrombosis and Haemostasis (SETH)-agreed on 12 controversial questions regarding prevention and management of CAT, which were thoroughly reviewed to provide further guidance. The suggestions presented herein may facilitate clinical decisions in specific complex circumstances, until these can be made leaning on reliable scientific evidence.
尽管在过去几年中，人们对癌症患者静脉血栓栓塞的兴趣日益浓厚，相关知识也有所增加，但仍有许多未解决的问题。由于现有文献的局限性，基于证据的临床实践指南无法针对癌症相关血栓形成（CAT）中常见的具有挑战性的情况给出可靠的建议。来自三个科学协会——西班牙内科协会（SEMI）、西班牙医学肿瘤学协会（SEOM）和西班牙血栓与止血协会（SETH）——的多学科专家小组就12个关于CAT预防和管理的争议性问题达成了一致意见，并对这些问题进行了全面审查以提供进一步指导。本文提出的建议可能会在特定复杂情况下促进临床决策，直到能够依据可靠的科学证据做出决策。
