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Occurrence of alkali-labile sites in pulse labelled DNA of Escherichia coli after the action of DNA-damaging chemicals.

作者信息

Slezáriková V, Sedliaková M

机构信息

Department of Molecular Genetics, Cancer Research Institute, Slovak Academy of Sciences, Bratislava, Czechoslovakia.

出版信息

Folia Microbiol (Praha). 1987;32(6):531-4. doi: 10.1007/BF02877202.

Abstract

UV irradiated E. coli cells contain alkali labile sites in their DNA daughter chains. It is shown here that the occurrence of alkali labile sites in the newly synthesized DNA is a more common phenomenon. It occurred after treatment with two different DNA damaging chemicals, but not after treatment with nalidixic acid.

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