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巨型肉孢子虫大囊胞提取物的促有丝分裂活性归因于凝集素。

The mitogenicity of extracts from Sarcocystis gigantea macrocysts is due to lectin(s).

作者信息

Montag T, Tietz H J, Brose E, Liebenthal C, Mann W, Hiepe T, Hiepe F, Coupek J

机构信息

Institut für Medizinische Mikrobiologie, Humboldt-Universität, Berlin, German Democratic Republic.

出版信息

Parasitol Res. 1987;74(2):112-5. doi: 10.1007/BF00536021.

DOI:10.1007/BF00536021
PMID:3125545
Abstract

As recently reported, extracts from macrocysts of Sarcocystis gigantea obtained by sonication show mitogenic activity towards lymphocytes. By affinity chromatography using a galactose gel, a lectin fraction which contained the entire mitogenic activity was obtained from these extracts.

摘要

最近有报道称，通过超声处理获得的巨型肉孢子虫大囊泡提取物对淋巴细胞具有促有丝分裂活性。通过使用半乳糖凝胶的亲和色谱法，从这些提取物中获得了具有全部促有丝分裂活性的凝集素组分。

相似文献

1
The mitogenicity of extracts from Sarcocystis gigantea macrocysts is due to lectin(s).巨型肉孢子虫大囊胞提取物的促有丝分裂活性归因于凝集素。
Parasitol Res. 1987;74(2):112-5. doi: 10.1007/BF00536021.
2
Determination of the mitogenic effect of Sarcocystis gigantea extracts in the lectin fraction.巨型肉孢子虫提取物在凝集素组分中的促有丝分裂作用的测定
Tokai J Exp Clin Med. 1986;11 Suppl:35-8.
3
Interactions between Sarcocystis gigantea lectin and toxin-containing fractions in human lymphocyte cultures.巨型肉孢子虫凝集素与人淋巴细胞培养物中含毒素组分之间的相互作用。
Parasitol Res. 1989;76(1):32-5. doi: 10.1007/BF00931068.
4
Isolation and characterization of a lectin from Sarcocystis gigantea.
Mol Biochem Parasitol. 1985 Sep;16(3):243-9. doi: 10.1016/0166-6851(85)90067-2.
5
Extracts from Sarcocystis gigantea macrocysts are mitogenic for human blood lymphocytes.来自巨型肉孢子虫大囊的提取物对人血淋巴细胞具有促有丝分裂作用。
Angew Parasitol. 1986 Nov;27(4):201-6.
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Sarcocystis gigantea lectin--mitogen and polyclonal B-cell activator.巨型肉孢子虫凝集素——促有丝分裂原和多克隆B细胞激活剂。
Parasitol Res. 1990;76(4):332-5. doi: 10.1007/BF00928188.
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Activation of human CD4+ and CD8+ cells by Sarcocystis gigantea lectin.巨型肉孢子虫凝集素对人CD4 +和CD8 +细胞的激活作用。
Parasitol Res. 1991;77(7):577-80. doi: 10.1007/BF00931016.
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Biophysical characterization of a mitogenic erythro- and lympho-agglutinating phytohemagglutinin (PPHA) of Phaseolus vulgaris.
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Mitogenicity of extracts from Sarcocystis gigantea on human and animal lymphocytes.
Tokai J Exp Clin Med. 1986;11 Suppl:31-4.

引用本文的文献

1
Interactions between Sarcocystis gigantea lectin and toxin-containing fractions in human lymphocyte cultures.巨型肉孢子虫凝集素与人淋巴细胞培养物中含毒素组分之间的相互作用。
Parasitol Res. 1989;76(1):32-5. doi: 10.1007/BF00931068.
2
Sarcocystis gigantea lectin--mitogen and polyclonal B-cell activator.巨型肉孢子虫凝集素——促有丝分裂原和多克隆B细胞激活剂。
Parasitol Res. 1990;76(4):332-5. doi: 10.1007/BF00928188.
3
Activation of human CD4+ and CD8+ cells by Sarcocystis gigantea lectin.巨型肉孢子虫凝集素对人CD4 +和CD8 +细胞的激活作用。

本文引用的文献

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Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
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2
Sarcocystis tenella: a lectin in muscle cysts.
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Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.从人血中分离单核细胞和粒细胞。通过一次离心分离单核细胞，通过离心和1g沉降相结合的方法分离粒细胞。
Parasitol Res. 1991;77(7):577-80. doi: 10.1007/BF00931016.
Scand J Clin Lab Invest Suppl. 1968;97:77-89.
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Isolation and characterization of a lectin from Sarcocystis gigantea.
Mol Biochem Parasitol. 1985 Sep;16(3):243-9. doi: 10.1016/0166-6851(85)90067-2.
5
Extracts from Sarcocystis gigantea macrocysts are mitogenic for human blood lymphocytes.来自巨型肉孢子虫大囊的提取物对人血淋巴细胞具有促有丝分裂作用。
Angew Parasitol. 1986 Nov;27(4):201-6.
6
B and T lymphocyte mitogenic properties in a snake venom.
Biomed Biochim Acta. 1986;45(4):459-66.
7
beta-Galactoside-binding muscle lectins of man and monkey show antigenic cross-reactions with those of bovine origin.人类和猴子的β-半乳糖苷结合性肌肉凝集素与牛源的β-半乳糖苷结合性肌肉凝集素存在抗原交叉反应。
Biochem J. 1979 Dec 1;183(3):755-8. doi: 10.1042/bj1830755.