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一例伴有脑转移的肾细胞癌患者的长期生存:病例报告

Long-term Survival in a Case of Renal Cell Carcinoma With Brain Metastases: A Case Report.

作者信息

Pooleri Ginil Kumar, Kleetus Jeeva Maria, Laddha Abhishek, Thomas Appu

机构信息

Department of Urology, Amrita Institute of Medical Sciences and Research Centre, Kochi, India.

出版信息

Clin Med Insights Case Rep. 2019 Jun 20;12:1179547619854703. doi: 10.1177/1179547619854703. eCollection 2019.

DOI:10.1177/1179547619854703
PMID:31258340
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6587384/
Abstract

Renal cell carcinoma with brain metastases is considered to have a poor prognosis. We are reporting a case of a 63-year-old male who showed excellent long term remission with a combination treatment of radiation and tyrosine kinase inhibitor for a solitary lesion in the brain, secondary to the renal tumor.

摘要

伴有脑转移的肾细胞癌被认为预后较差。我们报告一例63岁男性患者,其因肾肿瘤继发脑部孤立性病灶,经放疗和酪氨酸激酶抑制剂联合治疗后获得了长期良好缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be97/6587384/81ce8aa9cc83/10.1177_1179547619854703-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be97/6587384/0f42c254b5ca/10.1177_1179547619854703-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be97/6587384/81ce8aa9cc83/10.1177_1179547619854703-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be97/6587384/0f42c254b5ca/10.1177_1179547619854703-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/be97/6587384/81ce8aa9cc83/10.1177_1179547619854703-fig2.jpg

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本文引用的文献

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Multimodality treatment of brain metastases from renal cell carcinoma in the era of targeted therapy.靶向治疗时代肾细胞癌脑转移瘤的多模态治疗
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Brain metastasis in renal cancer patients: metastatic pattern, tumour-associated macrophages and chemokine/chemoreceptor expression.肾癌患者的脑转移:转移模式、肿瘤相关巨噬细胞和趋化因子/趋化受体表达。
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Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma.替西罗莫司、干扰素α或两者联合用于晚期肾细胞癌。
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Sorafenib in advanced clear-cell renal-cell carcinoma.索拉非尼治疗晚期透明细胞肾细胞癌
N Engl J Med. 2007 Jan 11;356(2):125-34. doi: 10.1056/NEJMoa060655.
8
Sunitinib versus interferon alfa in metastatic renal-cell carcinoma.舒尼替尼与干扰素α治疗转移性肾细胞癌的对比研究
N Engl J Med. 2007 Jan 11;356(2):115-24. doi: 10.1056/NEJMoa065044.