Jelavic Boris, Petricevic Josko, Marijanović Inga, Bevanda Milenko
Department of Otorhinolaryngology, University Hospital Mostar, Mostar, Bosnia and Herzegovina.
School of Medicine, University of Mostar, Mostar, Bosnia and Herzegovina.
Eurasian J Med. 2019 Jun;51(2):196-202. doi: 10.5152/eurasianjmed.2018.18192.
The bacteria () have been identified in the extragastric tissues in the head and neck. The origin and pathogenicity of these bacteria in the head and neck are not known. Gastric reflux and nasal or oral routes are the possible modes of spread. In many sinonasal, pharyngeal, laryngeal, and middle ear disorders, laryngopharyngeal reflux has been identified as a contributing or causative factor. One possible mode by which laryngopharyngeal reflux may contribute is by seeding of the extragastric mucosa with . The clinical significance of the discovery of in extragastric tissues in the head and neck is unclear. There is no evidence of a pathologic or active role of in otorhinolaryngological disorders. The suggestion that the sinonasal cavities and pharynx may serve as a reservoir for and that reinfection of the stomach occurs after eradication therapy awaits further studies for confirmation. No connection was observed between found in the stomach and found in the head and neck. Also, these bacteria, found in the head and neck tissues, may be accidental or innocent bystanders that do not affect the pathways of otolaryngological and gastroduodenal diseases. This review examines the evidence for a possible relationship of with otorhinolaryngological diseases.
已在头颈部的胃外组织中鉴定出 （）细菌。这些细菌在头颈部的起源和致病性尚不清楚。胃反流以及鼻腔或口腔途径是可能的传播方式。在许多鼻窦、咽、喉和中耳疾病中，喉咽反流已被确定为一个促成或致病因素。喉咽反流可能起作用的一种可能方式是通过 对胃外黏膜进行播散。在头颈部胃外组织中发现 的临床意义尚不清楚。没有证据表明 在耳鼻喉科疾病中具有病理或活跃作用。关于鼻窦腔和咽部可能作为 的储存库以及根除治疗后胃会再次感染的说法有待进一步研究证实。在胃中发现的 与在头颈部发现的 之间未观察到关联。此外，在头颈部组织中发现的这些细菌可能是偶然的或无害的旁观者，不会影响耳鼻喉科和胃十二指肠疾病的发病途径。本综述探讨了 与耳鼻喉科疾病可能存在关系的证据。
