Siupsinskiene N, Katutiene I, Jonikiene V, Janciauskas D, Vaitkus S
Faculty of Health Sciences,Klaipeda University,Kaunas,Lithuania.
ENT department,Klaipeda Republic Hospital,Kaunas,Lithuania.
J Laryngol Otol. 2017 Jun;131(6):549-556. doi: 10.1017/S0022215117000597. Epub 2017 Mar 20.
To identify Helicobacter pylori infection in tonsillar tissue samples from patients undergoing tonsillectomy for chronic tonsillitis versus tonsillar hypertrophy, and to assess the possible relationships between H pylori and patients' sociodemographic data and laryngopharyngeal reflux.
In this prospective study, 97 patients who underwent tonsillectomy were divided into the following 2 groups: patients with chronic tonsillitis (n = 62) and patients with tonsillar hypertrophy (control group; n = 35). H pylori infection in the tonsillar biopsy samples was identified using histochemical and rapid urease tests.
The incidence of H pylori infection was significantly higher in the chronic tonsillitis group (56.5 per cent) compared to the control group (31.4 per cent). Similar findings were obtained for both subgroups of adults (68.6 vs 42.3 per cent) and children (40.7 vs 0.0 per cent). Significant relationships between a positive H pylori finding and laryngopharyngeal reflux related signs of vocal fold oedema, diffuse laryngeal oedema and hypertrophy of the posterior commissure were revealed.
H pylori infection may be related to chronic tonsillitis and laryngopharyngeal reflux.
鉴别因慢性扁桃体炎或扁桃体肥大而接受扁桃体切除术患者的扁桃体组织样本中的幽门螺杆菌感染情况，并评估幽门螺杆菌与患者社会人口学数据及喉咽反流之间的可能关系。
在这项前瞻性研究中，97例接受扁桃体切除术的患者被分为以下两组：慢性扁桃体炎患者（n = 62）和扁桃体肥大患者（对照组；n = 35）。采用组织化学和快速尿素酶试验鉴定扁桃体活检样本中的幽门螺杆菌感染情况。
慢性扁桃体炎组的幽门螺杆菌感染发生率（56.5%）显著高于对照组（31.4%）。成人亚组（68.6%对42.3%）和儿童亚组（40.7%对0.0%）也得到了类似的结果。幽门螺杆菌检测呈阳性与喉咽反流相关的声带水肿、弥漫性喉水肿和后联合肥大体征之间存在显著关系。
幽门螺杆菌感染可能与慢性扁桃体炎和喉咽反流有关。
