Sher-I-Murtaza Muhammad, Baig Mirza Ahmad Raza
Dr. Muhammad Sher-i-Murtaza, (MBBS, FCPS). Assistant Professor of Cardiac Surgery, Ch. Pervaiz Elahi Institute of Cardiology (CPEIC), Multan, Pakistan.
Mr. Mirza Ahmad Raza Baig, (B. Sc. (Hons.) Cardiac Perfusion Technology), Clinical Perfusionist (Specialist), Cardiac Center at Hail Region, Hail, Saudi Arabia.
Pak J Med Sci. 2019;35(3):605-608. doi: 10.12669/pjms.35.3.988.
To evaluate the clinical safety of left internal mammary artery (LIMA) harvesting in hemodynamically unstable patients after establishing cardiopulmonary bypass (CPB) in isolated coronary artery bypass graft (CABG) surgery.
The prospective observational study was conducted at Chaudhry Pervaiz Elahi Institute of Cardiology, Multan, Pakistan, from December 2016 to August 2018. All patients undergoing isolated CABG surgery in which LIMA conduit was harvested after establishing cardiopulmonary bypass because of hemodynamic instability at induction of anaesthesia or during surgery were included in the study. Preoperative, operative and postoperative characteristics of the patients were recorded. Data was analyzed using SPSS 19.
In Forty nine patients including 39 male and 10 female, early CPB had to be established because of hemodynamic instability and afterwards LIMA was harvested. Out of 49, 30 patients presented with CCS class III angina. 37 (75.5%) patients were scheduled on elective coronary surgery waiting list. There were 39 (79.59%) patients who weaned off bypass on mild inotropic support and 4 (8.16%) patients needed IABP support. All patients had multi-vessel coronary artery disease. Mean number of grafts were 3.428±0.577, CPB time was 110.59±25.594 and hospital stay was 5.367±1.424.
The study showed that LIMA can be safely harvested in unstable patients after establishing extracorporeal circulation and by using this operative strategy in patients who need urgent or emergent surgical coronary revascularization LIMA can be safely used as a conduit.
评估在单纯冠状动脉旁路移植术(CABG)中,体外循环(CPB)建立后,从血流动力学不稳定患者身上获取左乳内动脉(LIMA)的临床安全性。
前瞻性观察性研究于2016年12月至2018年8月在巴基斯坦木尔坦的乔杜里·佩尔韦兹·埃拉希心脏病学研究所进行。所有接受单纯CABG手术的患者,因麻醉诱导期或手术期间血流动力学不稳定而在建立体外循环后获取LIMA导管的,均纳入本研究。记录患者术前、术中及术后特征。使用SPSS 19进行数据分析。
49例患者,包括39例男性和10例女性,因血流动力学不稳定而必须早期建立CPB,随后获取LIMA。49例患者中,30例表现为加拿大心血管学会(CCS)III级心绞痛。37例(75.5%)患者在择期冠状动脉手术等候名单上。39例(79.59%)患者在轻度血管活性药物支持下脱离体外循环,4例(8.16%)患者需要主动脉内球囊反搏(IABP)支持。所有患者均患有多支冠状动脉疾病。平均移植血管数为3.428±0.577,CPB时间为110.59±25.594,住院时间为5.367±1.424。
研究表明,在建立体外循环后,不稳定患者可安全获取LIMA,通过在需要紧急手术冠状动脉血运重建的患者中采用这种手术策略,LIMA可安全用作导管。