习惯性使用嚼烟者与非使用者的唾液白细胞介素-1β水平及临床牙周参数
Salivary Interleukin 1-beta levels and clinical periodontal parameters in habitual naswar users and non-users.
作者信息
Abbasi Zaeem Arif, Hadi Naila Irum, Zubairi Adnan Mustafa, Hosein Mervyn
机构信息
Dr. Zaeem Arif Abbasi, BDS., Ziauddin University, 4/B, Sharah-e-Ghalib, Block 6, Clifton, Karachi, Pakistan.
Prof. Dr. Naila Irum Hadi, Ph.D., M.Phil, MBBS. Islamabad Medical & Dental College, Murree Road, Satra Mile, Islamabad, Pakistan.
出版信息
Pak J Med Sci. 2019;35(3):674-679. doi: 10.12669/pjms.35.3.10.
OBJECTIVES
Aim of our study was to assess the expression of salivary Interleukin 1-beta (IL-1β) and clinical periodontal parameters in users and non-users (controls).
METHODS
Eighty four individuals (forty-two users and forty-two controls) were included in the study which was conducted between August 2017 and May 2018. Salivary IL-1β levels, plaque index (PI), bleeding on probing (BOP), probing depth (PD) and clinical attachment loss (CAL) was assessed in all the participants.
RESULTS
PD of 4mm (p<0.05), PD of 5-6mm (p<0.05), CAL (p<0.001) and levels of salivary IL-1β (p<0.05) were significantly higher among users as compared to controls while PI, BOP and number of missing teeth showed no significant difference among the two groups (p>0.05).
CONCLUSION
Periodontal inflammatory conditions were worse and salivary IL-1β levels were elevated in users as compared to controls.
目的
本研究旨在评估使用者和非使用者（对照组）唾液白细胞介素1β（IL-1β）的表达及临床牙周参数。
方法
本研究纳入了84名个体（42名使用者和42名对照组），研究于2017年8月至2018年5月进行。对所有参与者评估唾液IL-1β水平、菌斑指数（PI）、探诊出血（BOP）、探诊深度（PD）和临床附着丧失（CAL）。
结果
与对照组相比，使用者中4mm的PD（p<0.05）、5 - 6mm的PD（p<0.05）、CAL（p<0.001）和唾液IL-1β水平（p<0.05）显著更高，而PI、BOP和缺失牙数量在两组之间无显著差异（p>0.05）。
结论
与对照组相比，使用者的牙周炎症状况更差，唾液IL-1β水平升高。
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