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小脑共济失调作为甲状腺功能减退症的首发症状

CEREBELLAR ATAXIA AS A PRESENTING FEATURE OF HYPOTHYROIDISM.

作者信息

Kotwal S K, Kotwal S, Gupta R, Singh J B, Mahajan A

机构信息

Government Medical College Jammu, Medicine Department, Jammu, India.

Government Medical College Jammu, Pathology Department, Jammu, India.

出版信息

Acta Endocrinol (Buchar). 2016 Jan-Mar;12(1):77-79. doi: 10.4183/aeb.2016.77.

DOI:10.4183/aeb.2016.77
PMID:31258805
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6586745/
Abstract

CONTEXT

Besides its typical features, hypothyroidism comes to notice sometimes with neurologic features like reversible cerebellar ataxia, dementia, peripheral neuropathy, coma, etc. Therefore hypothyroidism should be suspected in all cases of cerebellar ataxia, as it is easily treatable.

OBJECTIVE

Here we illustrate a case of hypothyroidism initially reported with cerebellar ataxia.

CASE REPORT

A 40 year-old male presented with history of gait-ataxia. His investigations revealed frank primary hypothyroidism with positive anti-TPO antibody. The patient was put on thyroxine and he improved completely within eight weeks.

CONCLUSIONS

This case report emphasizes that hypothyroidism can present with ataxia as one of the initial features. Therefore, hypothyroidism should be considered in all cases of cerebellar ataxia as it is a reversible cause of ataxia.

摘要

背景

除了其典型特征外,甲状腺功能减退有时会表现出诸如可逆性小脑共济失调、痴呆、周围神经病变、昏迷等神经学特征。因此,在所有小脑共济失调病例中均应怀疑甲状腺功能减退,因为其易于治疗。

目的

在此,我们举例说明一例最初表现为小脑共济失调的甲状腺功能减退病例。

病例报告

一名40岁男性,有步态共济失调病史。其检查显示明显的原发性甲状腺功能减退且抗甲状腺过氧化物酶抗体呈阳性。该患者开始服用甲状腺素,八周内完全康复。

结论

本病例报告强调甲状腺功能减退可表现为共济失调作为初始特征之一。因此,在所有小脑共济失调病例中均应考虑甲状腺功能减退,因为它是共济失调的一个可逆病因。

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