Takahashi Paul Y, Quigg Stephanie M, Croghan Ivana T, Schroeder Darrell R, Ebbert Jon O
Division of Primary Care Internal Medicine, Mayo Clinic, Rochester, MN, USA.
Robert and Arlene Kogod Center on Aging, Mayo Clinic, Rochester, MN, USA.
SAGE Open Med. 2019 Jun 24;7:2050312119858042. doi: 10.1177/2050312119858042. eCollection 2019.
Clinicians recommend diet and exercise for overweight/obese patients. We conducted a secondary analysis of a randomized controlled clinical trial evaluating goal setting and pedometer use versus usual care on weight, waist circumference, and blood pressure of patients with multiple chronic conditions.
In this trial, we recruited and randomized patients over 18 years with multiple chronic conditions. There were two groups with an immediate intervention group who received behavioral coaching and a pedometer versus a delayed control who received the intervention after 2 months. We evaluated body weight, waist circumference, and blood pressure as outcomes. We used analysis of covariance to evaluate differences between the intervention and the control groups.
Of 130 patients, mean age was 63.4 years (SD, 17.3). At 2 months, intervention participants lost 0.2 kg versus a 0.1-kg gain in the control participants ( = .44). The immediate intervention group had significantly smaller waist circumference change at 2-month follow-up compared to control at -1.6 cm (95% confidence interval = -3.1 to -0.1), which was driven by an increase in waist circumference in the delayed control group. No difference in systolic blood pressure was observed.
We observed no difference in weight or blood pressure between the groups with obesity and multiple chronic conditions.
临床医生建议超重/肥胖患者进行饮食和运动。我们对一项随机对照临床试验进行了二次分析，该试验评估了目标设定和计步器使用与常规护理对患有多种慢性病患者的体重、腰围和血压的影响。
在该试验中，我们招募了18岁以上患有多种慢性病的患者并将其随机分组。有两组，一组是立即干预组，接受行为指导和计步器，另一组是延迟对照组，在2个月后接受干预。我们将体重、腰围和血压作为观察指标。我们使用协方差分析来评估干预组和对照组之间的差异。
130名患者的平均年龄为63.4岁（标准差为17.3）。在2个月时，干预组参与者体重减轻了0.2千克，而对照组参与者体重增加了0.1千克（P = 0.44）。在2个月的随访中，立即干预组的腰围变化明显小于对照组，为-1.6厘米（95%置信区间=-3.1至-0.1），这是由延迟对照组腰围增加所致。未观察到收缩压有差异。
我们观察到肥胖且患有多种慢性病的两组之间在体重或血压方面没有差异。
