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关于特应性皮炎患者使用外用糖皮质激素相关问题的知识。

The knowledge of issues associated with topical corticosteroids using in patients with atopic dermatitis.

作者信息

Jaworek Andrzej, Szafraniec Krystyna, Pastuszczak Maciej, Zalewski Adam, Wojas-Pelc Anna

机构信息

Department of Dermatology, Jagiellonian University, Collegium Medicum, Cracow, Poland.

Epidemiology and Population Studies Department, Institute of Public Health, Faculty of Health Sciences, Jagiellonian University, Cracow, Poland.

出版信息

Pol Merkur Lekarski. 2019 Jun 28;46(276):243-247.

Abstract

UNLABELLED

Atopic dermatitis (AD) is the most common inflammatory dermatitis, always accompanied by the pruritus. First line treatment comprise of topical steroids, however, there is a particular concern among patients with atopic dermatitis - "steroid phobia", which results in lack of efficacy of the therapy. Steroid phobia arises usually from insufficient knowledge of these drugs.

AIM

The aim of the study was to evaluate the knowledge of topical corticosteroids (TCS) and familiarity with so called safe therapy methods among atopic dermatitis patients.

MATERIALS AND METHODS

In the study participated 143 adult patients with AD diagnosis made by a specialist dermatologist-venereologist and allergist in accordance with Hanifin and Rajka's diagnostic criteria. Patients filled anonymously authorial survey which included questions concerning disease duration, severity of pruritus, frequency of skin lubrication, understanding of topical steroid therapy and practical aspects of safe TCS application.

RESULTS

Correct answers responding incidence to questions related to TCS diminished with the patients age, while on the other hand, it increased statistically significantly with the level of education. What responders were afraid of most frequently were the skin atrophy (56,6%), cataract (52,4%) and teleangiectasias (44,8%), in opposite to neoplasms (16,8%) and obesity (22,4%). Concerns were dependent to the treating physician- patients under the care of dermatologists more often were worried about the skin atrophy, teleangiectasias and cataract. Among participating patients just 3,5% of them (5 patients) knew the finger tip unit term, whereas the majority (56%) had been informed about safe TCS therapy methods. Amidst respondents who answered questions about TCS correctly statistically significantly lower pruritus intensity was observed.

CONCLUSIONS

Results of our study indicate on necessity of taking action to improve cooperation between patients and doctors insofar as topical therapy of atopic dermatitis.

摘要

未标注

特应性皮炎(AD)是最常见的炎症性皮肤病,常伴有瘙痒。一线治疗包括外用糖皮质激素,然而,特应性皮炎患者存在一个特殊问题——“激素恐惧症”,这导致治疗效果不佳。激素恐惧症通常源于对这些药物的了解不足。

目的

本研究旨在评估特应性皮炎患者对外用糖皮质激素(TCS)的了解以及对所谓安全治疗方法的熟悉程度。

材料与方法

143名成年患者参与了本研究,这些患者由皮肤科性病专家和过敏症专科医生根据Hanifin和Rajka的诊断标准确诊为AD。患者匿名填写了作者设计的调查问卷,其中包括有关病程、瘙痒严重程度、皮肤润滑频率、对外用激素治疗的理解以及安全应用TCS的实际问题。

结果

与TCS相关问题的正确回答发生率随患者年龄增长而降低,另一方面,随教育程度的提高而显著增加。应答者最常担心的是皮肤萎缩(56.6%)、白内障(52.4%)和毛细血管扩张(44.8%),而对肿瘤(16.8%)和肥胖(22.4%)的担忧较少。担忧程度与治疗医生有关——在皮肤科医生照料下的患者更常担心皮肤萎缩、毛细血管扩张和白内障。在参与研究的患者中,只有3.5%(5名患者)知道指尖单位这个术语,而大多数(56%)已被告知安全的TCS治疗方法。在正确回答有关TCS问题的受访者中,观察到瘙痒强度在统计学上显著较低。

结论

我们的研究结果表明,在特应性皮炎的外用治疗方面,有必要采取行动改善医患合作。

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