夜间低氧对阻塞性睡眠呼吸暂停患者夜尿症的影响。
Effect of Nocturnal Hypoxia on Nocturia in Patients With Obstructive Sleep Apnea.
作者信息
Chung Jae Hoon, Moon Hong Sang, Park Sung Yul, Kim Kyung Rae, Cho Seok Hyun, Kim Yong Tae
机构信息
Department of Urology, Hanyang University College of Medicine, Seoul, Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul, Korea.
出版信息
Int Neurourol J. 2019 Jun;23(2):161-168. doi: 10.5213/inj.1938026.013. Epub 2019 Jun 30.
PURPOSE
To identify the association between nocturia and obstructive sleep apnea (OSA), we compared results of polysomnography (PSG) with the presence or absence of nocturia in patients with suspected OSA.
METHODS
Patients underwent PSG for suspected OSA. The International Prostate Symptom Score and quality of life (IPSS/QoL) questionnaire was evaluated to assess voiding symptoms that may affect sleep quality. The results of PSG were compared between patient groups with or without nocturia.
RESULTS
In logistic regression analysis, age (odds ratio [OR], 1.052; P=0.004), diabetes mellitus (OR, 6.675; P<0.001), mean O2 saturation (OR, 0.650; P=0.017), oxygen desaturation index (ODI) 3 (OR, 1.193; P=0.010), and ODI4 (OR, 1.136; P=0.014) affected nocturia independently among the OSA-suspected patients.
CONCLUSION
Hypoxia caused by OSA affects the incidence of nocturia. Less desaturated OSA patients with nocturia may require more urological evaluation and treatment for nocturia even after the correction of OSA.
目的
为了确定夜尿症与阻塞性睡眠呼吸暂停（OSA）之间的关联，我们比较了疑似OSA患者的多导睡眠图（PSG）结果与是否存在夜尿症的情况。
方法
对疑似OSA的患者进行PSG检查。评估国际前列腺症状评分和生活质量（IPSS/QoL）问卷，以评估可能影响睡眠质量的排尿症状。比较有或没有夜尿症的患者组之间的PSG结果。
结果
在逻辑回归分析中，年龄（比值比[OR]，1.052；P = 0.004）、糖尿病（OR，6.675；P < 0.001）、平均氧饱和度（OR，0.650；P = 0.017）、氧去饱和指数（ODI）3（OR，1.193；P = 0.010）和ODI4（OR，1.136；P = 0.014）在疑似OSA患者中独立影响夜尿症。
结论
OSA引起的缺氧影响夜尿症的发生率。即使在OSA得到纠正后，夜间尿症且氧饱和度较低的OSA患者可能需要更多的泌尿科评估和治疗夜尿症。
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