Ruokonen J, Sandelin K, Mäkinen J
Ann Otol Rhinol Laryngol. 1979 Mar-Apr;88(2 Pt 1):166-71. doi: 10.1177/000348947908800203.
At adenoidectomy specimens for bacteriological, virological, and histological investigation were obtained from the adenoids of 144 children, 53 of whom suffered from otitis media with effusion, or frequently recurring otitis media. Comparison of findings in children with ear diseases with those obtained in the rest of the material showed that Hemophilus influenza was cultured from 50% of the specimens from the children with ear diseases, while only 14% of the cultures from the other children yielded H. influenza. Virus isolates were made from 17 adenoids. In children with ear diseases a virus was isolated from 28% of the specimens, whereas positive isolates were obtained in only 3% of the rest of the speciemens. Both findings are statistically significant and support the view that the adenoid tissue may play an important role in the etiology of otitis media with effusion. The infected adenoid may be the direct source of the primary infections, or continuous microbial irritation in the nasopharynx may indirectly be the cause of otitis media with effusion, as persistent infection and edema maintain chronic dysfunction of the eustachian tube. Thus adenoidectomy may be beneficial in the treatment of frequently recurring otitis media, preventing otitis media with effusion from developing.
在腺样体切除术时,从144名儿童的腺样体获取标本进行细菌学、病毒学和组织学研究,其中53名儿童患有分泌性中耳炎或复发性中耳炎。将患耳病儿童的研究结果与其他儿童的结果进行比较发现,患耳病儿童的标本中有50%培养出流感嗜血杆菌,而其他儿童的培养物中只有14%培养出流感嗜血杆菌。从17个腺样体中分离出病毒。患耳病儿童的标本中有28%分离出病毒,而其他标本中只有3%分离出病毒呈阳性。这两项结果均具有统计学意义,支持腺样体组织可能在分泌性中耳炎的病因学中起重要作用这一观点。受感染的腺样体可能是原发性感染的直接来源,或者鼻咽部持续的微生物刺激可能间接导致分泌性中耳炎,因为持续感染和水肿会维持咽鼓管的慢性功能障碍。因此,腺样体切除术可能有助于治疗复发性中耳炎,预防分泌性中耳炎的发生。