黑腹果蝇中读取六个丝氨酸密码子的三种tRNA（Ser）的核苷酸序列。
Nucleotide sequences of three tRNA(Ser) from Drosophila melanogaster reading the six serine codons.
作者信息
Cribbs D L, Gillam I C, Tener G M
机构信息
Department of Biochemistry, University of British Columbia, Vancouver, Canada.
出版信息
J Mol Biol. 1987 Oct 5;197(3):389-95. doi: 10.1016/0022-2836(87)90552-3.
The nucleotide sequences of three serine tRNAs from Drosophila melanogaster, together capable of decoding the six serine codons, were determined. tRNA(Ser)2b has the anticodon GCU, tRNA(Ser)4 has CGA and tRNA(Ser)7 has IGA. tRNA(Ser)2b differs from the last two by about 25%. However, tRNA(Ser)4 and tRNA(Ser)7 are 96% homologous, differing only at the first position of the anticodon and two other sites. This unusual sequence relationship suggests, together with similar pairs in the yeasts Schizosaccharomyces pombe and Saccharomyces cerevisiae, that eukaryotic tRNA(Ser)UCN may be undergoing concerted evolution.
测定了来自黑腹果蝇的三种丝氨酸tRNA的核苷酸序列，它们共同能够解码六个丝氨酸密码子。tRNA(Ser)2b的反密码子为GCU，tRNA(Ser)4的反密码子为CGA，tRNA(Ser)7的反密码子为IGA。tRNA(Ser)2b与后两者的差异约为25%。然而，tRNA(Ser)4和tRNA(Ser)7的同源性为96%，仅在反密码子的第一位和其他两个位点存在差异。这种不同寻常的序列关系，与粟酒裂殖酵母和酿酒酵母中类似的配对情况一起表明，真核生物的tRNA(Ser)UCN可能正在经历协同进化。
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