Detection of T and B cell populations in some lymphoproliferative disorders.

In patients with plasmocytoma, leukemic lymphoma, hairy-cell leukemia and chronic lymphocytic leukemia the state of T and B lymphocyte population was determined by rosette tests for the demonstration of receptors for Fc fragment of immunoglobulins as well as receptors for the third component of the complement, and by immunofluorescence demonstration of membrane immunoglobulins. The results confirm that for reliable determination of pathologic proliferation of peripheral blood lymphocytes in the above diseases not only membrane immunoglobulin should be detected but also rosette tests are necessary.