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乳腺癌转移导致胃出口梗阻的罕见表现:一例报告

Unusual Presentation of Gastric Outlet Obstruction Due to Breast Cancer Metastasis: A Case Report.

作者信息

Mohy-Ud-Din Nabeeha, Patek Bonnie, Dhawan Manish

机构信息

Internal Medicine, Allegheny Health Network, Pittsburgh, USA.

Gastroenterology and Hepatology, Allegheny Health Network, Pittsburgh, USA.

出版信息

Cureus. 2019 Apr 24;11(4):e4533. doi: 10.7759/cureus.4533.

DOI:10.7759/cureus.4533
PMID:31263641
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6592458/
Abstract

Gastric outlet obstruction can be caused by various pathologies, including peptic ulcer disease, gastric polyps, and malignancies. The incidence rate of breast cancer metastasis to the stomach is only 0.3%. We describe a rare case of an 83-year-old female with a remote history of breast cancer who presented with symptoms of nausea and vomiting. She underwent an upper endoscopy, and biopsies revealed chronic gastritis. However, when she presented for the second time with similar symptoms, she underwent endoscopic ultrasound (EUS)-guided biopsies, which clinched the diagnosis of breast cancer metastasis causing gastric outlet obstruction. This case describes the importance of keeping a wide differential diagnosis for the causes of gastric outlet obstruction and the significance of deeper EUS-guided biopsies if initial endoscopic biopsies are inconclusive.

摘要

胃出口梗阻可由多种病变引起,包括消化性溃疡病、胃息肉和恶性肿瘤。乳腺癌转移至胃的发生率仅为0.3%。我们描述了一例罕见病例,一名83岁女性,有乳腺癌病史,出现恶心和呕吐症状。她接受了上消化道内镜检查,活检显示为慢性胃炎。然而,当她再次出现类似症状时,接受了内镜超声(EUS)引导下活检,确诊为乳腺癌转移导致胃出口梗阻。该病例说明了对胃出口梗阻病因进行广泛鉴别诊断的重要性,以及如果初始内镜活检结果不明确,进行更深层次EUS引导下活检的意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/a4569c2f50ad/cureus-0011-00000004533-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/6fcc1c884093/cureus-0011-00000004533-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/f37d2fa5b3d9/cureus-0011-00000004533-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/a10946cc42e8/cureus-0011-00000004533-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/a4569c2f50ad/cureus-0011-00000004533-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/6fcc1c884093/cureus-0011-00000004533-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/f37d2fa5b3d9/cureus-0011-00000004533-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/a10946cc42e8/cureus-0011-00000004533-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fe4/6592458/a4569c2f50ad/cureus-0011-00000004533-i04.jpg

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本文引用的文献

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2
Breast Cancer Metastasis to the Stomach That Was Diagnosed after Endoscopic Submucosal Dissection.内镜下黏膜下剥离术后诊断出的乳腺癌胃转移
Case Rep Gastrointest Med. 2016;2016:2085452. doi: 10.1155/2016/2085452. Epub 2016 Nov 9.
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Clinicopathological features of gastric metastasis from breast cancer in three cases.
Medicine (Baltimore). 2020 Nov 25;99(48):e22527. doi: 10.1097/MD.0000000000022527.
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Secondary Alopecia Neoplastica Mimicking Alopecia Areata following Breast Cancer.乳腺癌后酷似斑秃的继发性肿瘤性脱发
Case Rep Oncol. 2020 Jun 11;13(2):627-632. doi: 10.1159/000507694. eCollection 2020 May-Aug.
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Gastric metastases originating from breast cancer: report of 8 cases and review of the literature.胃癌转移灶源于乳腺癌:8 例报告及文献复习。
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Gastric outlet obstruction with benign endoscopic biopsy should be further explored for malignancy.对于伴有良性内镜活检的胃出口梗阻,应进一步排查是否存在恶性肿瘤。
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Malignancy is the most common cause of gastric outlet obstruction in the era of H2 blockers.在H2阻滞剂时代,恶性肿瘤是胃出口梗阻最常见的原因。
Am J Gastroenterol. 1995 Oct;90(10):1769-70.
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