Skafida Efthymia, Triantafyllopoulou Ioanna, Flessas Ioannis, Liontos Michael, Koutsoukos Konstantinos, Zagouri Flora, Dimopoulos Athanasios-Meletios
Haematology-Oncology Unit, Department of Clinical Therapeutics, National and Kapodistrian University of Athens, Alexandra General Hospital, Athens, Greece.
General and Breast Surgery Unit, General and Maternity Hospital "Helena Venizelou,", Athens, Greece.
Case Rep Oncol. 2020 Jun 11;13(2):627-632. doi: 10.1159/000507694. eCollection 2020 May-Aug.
Cutaneous metastases from visceral carcinomas are relatively uncommon, with an overall incidence ranging from 0.7 to 9%. Diagnosis of scalp metastases usually escapes clinicians and dermatologists due to the fact that these metastases are mimicking other benign dermatological conditions. Herein, we present an uncommon case of scalp alopecia neoplastica mimicking alopecia areata due to breast cancer; a 43-year-old woman diagnosed with lobular cancer 3 years previously presented with acute loss of hair in well-circumscribed areas of the scalp and was diagnosed with alopecia areata by a private-practice dermatologist. She was then reevaluated, and due to her history of breast cancer, a biopsy from the scalp was performed and revealed alopecia neoplastica. At the same time that the skin lesions were recognized as disease involvement, the patient presented with dyspepsia, and endoscopy of the upper and lower gastrointestinal tract also revealed metastasis to the stomach and bowel. Gastrointestinal metastasis may occur with several types of cancer, but the stomach and bowel are rare metastatic sites for breast cancer.
内脏癌的皮肤转移相对少见，总体发病率在0.7%至9%之间。头皮转移的诊断通常会逃过临床医生和皮肤科医生的注意，因为这些转移灶会模仿其他良性皮肤病。在此，我们报告一例罕见的因乳腺癌导致的模仿斑秃的头皮肿瘤性脱发病例；一名3年前被诊断为小叶癌的43岁女性，头皮出现边界清晰区域的急性脱发，一名私人执业皮肤科医生诊断为斑秃。随后她接受了重新评估，由于她有乳腺癌病史，对头皮进行了活检，结果显示为肿瘤性脱发。在皮肤病变被确认为疾病累及的同时，患者出现消化不良，上下消化道内镜检查还显示胃和肠道有转移。胃肠道转移可能发生在几种类型的癌症中，但胃和肠道是乳腺癌罕见的转移部位。
