基于两步级联传感反应构建一种用于选择性检测单线态氧的高灵敏度、大浓度范围荧光探针。
Construction of a fluorescent probe for selectively detecting singlet oxygen with a high sensitivity and large concentration range based on a two-step cascade sensing reaction.
作者信息
Long Lingliang, Yuan Xiangqi, Cao Siyu, Han Yuanyuan, Liu Weiguo, Chen Qian, Gong Aihua, Wang Kun
机构信息
School of Chemistry and Chemical Engineering, Jiangsu University, Zhenjiang, Jiangsu 212013, P. R. China.
School of Medicine, Jiangsu University, Zhenjiang, Jiangsu 212013, P. R. China.
出版信息
Chem Commun (Camb). 2019 Jul 25;55(58):8462-8465. doi: 10.1039/c9cc04300d. Epub 2019 Jul 2.
A novel fluorescent probe XQ-1 for selectively detecting O on the basis of a two-step cascade reaction has been rationally constructed. The probe responded to O not only showing a high sensitivity, but also displaying a large concentration range, which means that the probe can be used as a powerful tool to monitor the efficacy of PDT toward cancer and concurrently track the adverse effects on healthy cells.
一种基于两步级联反应选择性检测单线态氧（¹O₂）的新型荧光探针XQ-1已被合理构建。该探针对¹O₂做出响应，不仅显示出高灵敏度，而且呈现出较大的浓度检测范围，这意味着该探针可作为一种强大的工具，用于监测光动力疗法（PDT）对癌症的治疗效果，并同时追踪其对健康细胞的不良影响。
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