Al-Kandari S, Nordenfelt E, Al-Nakib B, Radakrishnan S, Al-Nakib W
Infectious Disease Hospital, Kuwait.
Scand J Infect Dis. 1987;19(6):611-6. doi: 10.3109/00365548709117194.
In a prospective study of acute hepatitis in Kuwait covering the period February 1983 to January 1984, a total of 1781 cases were diagnosed as having an acute viral hepatitis. 1,384 (77.7%) were found to be due to hepatitis A virus (HAV), 206 (11.5%) hepatitis B virus (HBV), 8 (0.4%) coinfection with HBV and delta virus (HDV), 8 (0.4%) superinfection of HDV on chronic HBsAg carriers and 157 (9%) non-A, non-B virus (NANB). 13 cases of CMV and 5 of EBV infections were also diagnosed. NANB viral hepatitis was a disease of young adults (mean age 29 years) with a male-female ratio of 3:1. A high incidence was noted among males from the Indian subcontinent (29.1/100,000 of population, compared to 5.4/100,000 among local Arabs), the majority of whom gave a history of recent visit to the Indian subcontinent. The clinical features and biochemical findings of acute NANB infection were found to be less severe than those of acute HBV infection and similar to acute HAV infection. Three patients (2.3%) with acute NANB virus infection developed chronic hepatitis (all women), and another 3 patients died because of fulminant hepatitis.
在一项对科威特1983年2月至1984年1月期间急性肝炎的前瞻性研究中，共诊断出1781例急性病毒性肝炎病例。其中1384例（77.7%）由甲型肝炎病毒（HAV）引起，206例（11.5%）由乙型肝炎病毒（HBV）引起，8例（0.4%）为HBV与丁型肝炎病毒（HDV）合并感染，8例（0.4%）为HDV在慢性HBsAg携带者中的重叠感染，157例（9%）为非甲非乙型病毒（NANB）感染。还诊断出13例巨细胞病毒感染和5例EB病毒感染。NANB病毒性肝炎是一种年轻人的疾病（平均年龄29岁），男女比例为3:1。在来自印度次大陆的男性中发病率较高（29.1/10万人口，而当地阿拉伯人为5.4/10万），其中大多数人有近期访问印度次大陆的病史。发现急性NANB感染的临床特征和生化检查结果不如急性HBV感染严重，与急性HAV感染相似。3例急性NANB病毒感染患者（2.3%）发展为慢性肝炎（均为女性），另有3例患者因暴发性肝炎死亡。
