Intonazzo V, La Rosa G, Lanza A, Famà B, Romano N, Farinella E
J Med Virol. 1983;12(4):247-51. doi: 10.1002/jmv.1890120404.
Aetiological studies were carried out on 407 cases of acute viral hepatitis during two consecutive years in two general hospitals in Palermo, Sicily. Two hundred ninety-seven showed serological evidence of hepatitis A virus (HAV) infection and 73 of hepatitis B virus (HBV) infection. Of the remaining 37, two had a serologically diagnosed cytomegalovirus hepatitis, while 35 were classified as non-A, non-B (NANB) hepatitis. The frequency of the different major agents of acute viral hepatitis was notably influenced by the age of the patients, HAV being prevalent in children and HBV and NANB in adults. About one-fourth of the adult cases of sporadic, acute viral hepatitis were attributed to NANB virus(es). The acute disease appeared less severe than B hepatitis, as indicated by the duration of jaundice, peak serum bilirubin, and aminotransferase levels. No history of drug addiction or of parenteral exposure to blood or blood products was obtained from the presumed NANB hepatitis patients.
在西西里岛巴勒莫的两家综合医院，连续两年对407例急性病毒性肝炎病例进行了病因学研究。297例显示有甲型肝炎病毒（HAV）感染的血清学证据，73例有乙型肝炎病毒（HBV）感染的血清学证据。其余37例中，2例经血清学诊断为巨细胞病毒性肝炎，35例归类为非甲非乙型（NANB）肝炎。急性病毒性肝炎不同主要病原体的发生率受患者年龄的显著影响，HAV在儿童中流行，HBV和NANB在成人中流行。散发性急性病毒性肝炎的成人病例中约四分之一归因于NANB病毒。从黄疸持续时间、血清胆红素峰值和转氨酶水平来看，急性疾病似乎不如乙型肝炎严重。在疑似NANB肝炎患者中，未发现药物成瘾史或经肠道外接触血液或血液制品的病史。
