移动电话传递的权变管理干预措施促进物质使用障碍个体的行为改变:一项荟萃分析。

Mobile telephone-delivered contingency management interventions promoting behaviour change in individuals with substance use disorders: a meta-analysis.

机构信息

King's College London, The National Addiction Centre, London, UK.

Department of Mental Health and Social Work, Middlesex University, London, UK.

出版信息

Addiction. 2019 Nov;114(11):1915-1925. doi: 10.1111/add.14725. Epub 2019 Jul 27.

Abstract

BACKGROUND/AIMS: Contingency management (CM) interventions have gained considerable interest due to their success in the treatment of addiction. However, their implementation can be resource-intensive for clinical staff. Mobile telephone-based systems might offer a low-cost alternative. This approach could facilitate remote monitoring of behaviour and delivery of the reinforcer and minimize issues of staffing and resources. This systematic review and meta-analysis assessed the evidence for the effectiveness of mobile telephone-delivered CM interventions to promote abstinence (from drugs, alcohol and tobacco), medication adherence and treatment engagement among individuals with substance use disorders.

DESIGN

A systematic search of databases (PsychINFO, CINAHL, MEDLINE PubMed, CENTRAL, Embase) for randomized controlled trials and within-subject design studies (1995-2019). The review was conducted in accordance with the PRISMA statement. The protocol was registered on PROSPERO.

SETTING

All included studies originated in the United states.

PARTICIPANTS

Seven studies were found, including 222 participants; two targeted alcohol abstinence among frequent drinkers and four targeted smoking cessation (in homeless veterans and those with post-traumatic stress disorder). One targeted medication adherence.

MEASURES

The efficacy of CM to increase alcohol and nicotine abstinence was compared with control using several outcomes; percentage of negative samples (PNS), quit rate (QR) and longest duration abstinent (LDA) at the end of the intervention.

FINDINGS

The random-effects meta-analyses produced pooled effect sizes of; PNS [d = 0.94, 95% confidence interval (CI) = 0.63-1.25], LDA (d = 1.08, 95% CI = 0.69-1.46) and QR (d = 0.46, 95% CI = 0.27-0.66), demonstrating better outcomes across the CM conditions. Most of the studies were rated as of moderate quality. 'Fail-safe N' computations for PNS indicated that 50 studies would be needed to produce a non-significant overall effect size. None could be calculated for QR and LDA due to insufficient number of studies.

CONCLUSION

Mobile telephone-delivered contingency management performs significantly better than control conditions in reducing tobacco and alcohol use among adults not in treatment for substance use disorders.

摘要

背景/目的:由于在治疗成瘾方面取得了成功,应急管理(CM)干预措施引起了相当大的关注。然而,它们的实施可能会对临床工作人员造成资源密集型的负担。基于移动电话的系统可能提供一种低成本的替代方案。这种方法可以促进对行为的远程监测,并提供强化物,最大限度地减少人员配备和资源问题。本系统评价和荟萃分析评估了移动电话传递 CM 干预措施在促进药物、酒精和烟草戒除、药物依从性和治疗参与方面的有效性,以促进药物使用障碍个体的康复。

设计

对数据库(心理信息学、CINAHL、MEDLINE PubMed、CENTRAL、Embase)进行系统搜索,以查找随机对照试验和个体内设计研究(1995-2019 年)。该综述符合 PRISMA 声明进行。该方案已在 PROSPERO 上注册。

地点

所有纳入的研究均源自美国。

参与者

共发现 7 项研究,包括 222 名参与者;其中 2 项针对频繁饮酒者的酒精戒除,4 项针对戒烟(在无家可归的退伍军人和创伤后应激障碍患者中)。1 项针对药物依从性。

措施

使用几种结果比较 CM 增加酒精和尼古丁戒除的效果与对照组:干预结束时的阴性样本百分比(PNS)、戒烟率(QR)和最长持续禁欲时间(LDA)。

结果

随机效应荟萃分析产生了汇总效应大小:PNS[d=0.94,95%置信区间(CI)=0.63-1.25]、LDA[d=1.08,95%CI=0.69-1.46]和 QR[d=0.46,95%CI=0.27-0.66],表明 CM 条件下的结果更好。大多数研究的质量被评为中等。对于 PNS,“安全 N”计算表明,需要 50 项研究才能产生非显著的总体效果量。由于研究数量不足,无法对 QR 和 LDA 进行计算。

结论

在减少未接受药物使用障碍治疗的成年人的烟草和酒精使用方面,移动电话传递的应急管理比对照组效果显著更好。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6617/6852192/8170e278ee31/ADD-114-1915-g001.jpg

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