Spirin A
Institute of Protein Research, Academy of Sciences of the U.S.S.R., Pushchino, Moscow Region.
Biochimie. 1987 Sep;69(9):949-56. doi: 10.1016/0300-9084(87)90228-8.
Three types of conformational changes in the translating ribosome are considered: (1) intersubunit movement (ribosome unlocking) during translocation; (2) L7/L12 stalk mobility affected by elongation factors; (3) change of tRNA residue during its transition from the A-site to the P-site. Relevant experimental data are reviewed.
(1) 转位过程中的亚基间移动(核糖体解锁);(2) 受延伸因子影响的L7/L12柄的流动性;(3) tRNA残基从A位点到P位点转变过程中的变化。文中回顾了相关实验数据。