Wyld R, Nimmo W S
Department of Anaesthesia, University of Sheffield.
Br Med J (Clin Res Ed). 1988 Mar 12;296(6624):744. doi: 10.1136/bmj.296.6624.744.
Periods of fasting perioperatively make normal drug treatment difficult to maintain. One hundred and seventy patients admitted consecutively for operations (excluding those having cardiac, neurosurgical, and orthopaedic operations) were studied to identify whether they received their prescribed drugs. Seventy two were receiving drugs unrelated to their operation or anaesthesia. One thousand seven hundred and forty six single prescriptions (that is, single doses) were recorded as to be given on the day of surgery and the next day, of which 256 (15%) were not administered. All prescriptions of analgesics and premedicants were given; when these were excluded the proportion of prescriptions that were not given rose to 29%. The prescriptions omitted included 38 out of 95 for drugs for cardiovascular disease, 34 out of 103 for drugs for respiratory disease, and 10 out of 61 for drugs for endocrine disorders. The omission of drugs was not known to the medical staff and may introduce variability in the response of patients perioperatively.
围手术期禁食会使正常的药物治疗难以维持。对连续收治的170例接受手术的患者（不包括接受心脏、神经外科和骨科手术的患者）进行了研究，以确定他们是否服用了 prescribed 药物。72例患者正在服用与手术或麻醉无关的药物。记录了1746份单剂量处方（即单次剂量），这些处方应在手术当天和第二天服用，其中256份（15%）未给药。所有镇痛剂和术前用药的处方均已给药；排除这些处方后，未给药的处方比例升至29%。遗漏的处方包括95份心血管疾病药物处方中的38份、103份呼吸系统疾病药物处方中的34份以及61份内分泌疾病药物处方中的10份。医务人员并不知晓药物遗漏情况，这可能会导致患者围手术期反应出现差异。
