Allen D G, Nymeyer D
Can J Comp Med. 1983 Apr;47(2):112-7.
A technique for the determination of cardiac output in the cat by the thermal dilution method is described. The values of cardiac output assessed by thermal dilution and the values of left ventricular function assessed echocardiographically are compared. Values of cardiac output obtained by thermal dilution compare favourably with values obtained by other investigators by indicator dye dilution, the Fick method and electromagnetic flowmeter technique. The technique of thermal dilution in the cat was consistent and simple to perform. The calculation of ventricular volumes and cardiac output echocardiographically using formulae suggested in man was unsuccessful. Such formulae based on assumptions of cardiac shape and contractility do not appear valid in the cat. Statistical analysis demonstrated a positive correlation between the cardiac output determined by thermodilution and the left ventricular diastolic and systolic dimensions determined echocardiographically. A positive correlation was also shown between the cardiac output and the cardiac index, the left ventricular diastolic dimension and the left ventricular systolic dimension and the percent change in minor diameter and the velocity of circumferential fibre shortening. A negative correlation existed between the left ventricular systolic dimension and the velocity of circumferential fibre shortening and the ejection time and the velocity of circumferential fibre shortening.
本文描述了一种通过热稀释法测定猫心输出量的技术。比较了通过热稀释评估的心输出量值和通过超声心动图评估的左心室功能值。通过热稀释获得的心输出量值与其他研究者通过指示剂稀释、菲克法和电磁流量计技术获得的值相比具有优势。猫的热稀释技术操作一致且简单。使用人类建议的公式通过超声心动图计算心室容积和心输出量未获成功。这种基于心脏形状和收缩性假设的公式在猫中似乎无效。统计分析表明,通过热稀释测定的心输出量与通过超声心动图测定的左心室舒张和收缩维度之间呈正相关。心输出量与心脏指数、左心室舒张维度、左心室收缩维度、短径百分比变化以及圆周纤维缩短速度之间也呈正相关。左心室收缩维度与圆周纤维缩短速度、射血时间与圆周纤维缩短速度之间呈负相关。