从 中分离得到的一株内生真菌中得到的两种新的邻苯二甲酸衍生物。
Two new phthalide derivatives from the endophytic fungus isolated from .
机构信息
State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources, College of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin, P. R. China.
出版信息
Nat Prod Res. 2021 Feb;35(3):421-427. doi: 10.1080/14786419.2019.1636237. Epub 2019 Jul 5.
Two new phthalide derivatives, (-)-3-carboxypropyl-7-hydroxyphthalide () and (-)-3-carboxypropyl-7-hydroxyphthalide methyl ester (), were isolated from the endophytic fungus isolated from the Chinese medicinal plant . Their structures were elucidated using spectroscopic methods, mainly on 1D and 2D NMR. Compound exhibited medium antibacterial activities against and with MIC values of 12.5-25 μg/mL, and showed a medium inhibition to with MIC value of 12.5 μg/mL.
从中国药用植物 中分离得到的内生真菌 中分离得到了两种新的邻苯二甲酸酯衍生物，(-)-3-羧丙基-7-羟基邻苯二甲酸酯()和(-)-3-羧丙基-7-羟基邻苯二甲酸甲酯()。它们的结构通过光谱方法，主要是 1D 和 2D NMR 来阐明。化合物 对 和 表现出中等的抗菌活性，MIC 值为 12.5-25μg/mL， 对 表现出中等的抑制活性，MIC 值为 12.5μg/mL。
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