Pan Jingjing, Wu Lian, Wang Huichuan, Lei Tao, Hu Bin, Xue Xiaorong, Li Qiongge
Department of Pharmacy, Xi'an Fourth Hospital.
Xi'an Forth Hospital Affiliated Northwestern Polytechnical University.
Medicine (Baltimore). 2019 Jul;98(27):e16116. doi: 10.1097/MD.0000000000016116.
To assess the adherence level of antihypertensive treatment and identify any associated risk factors in a sample of hypertensive patients from China.A cross-sectional study involving 488 Chinese hypertensive patients was conducted in a tertiary hospital in Xi'an, China. Data were collected regarding socio-demographic factors and hypertension-related clinical characteristics. The adherence to treatment was assessed using the previously validated instrument: therapeutic adherence scale for hypertensive patients.A total of 27.46% of patients were compliant with their antihypertensive treatments. Three factors were identified to be independently associated with antihypertensive treatment adherence: gender (P = .034), residence (P = .029), duration of high blood pressure (P < .001). Gender, residence, occupation, and the duration of antihypertensive drugs treatment used were found to have significant effects on treatment adherence in certain categories.Treatment adherence among hypertensive patients in China was poor. More attention and effective strategies should be designed to address factors affecting treatment adherence. Education about hypertension knowledge should be strengthened for patients. Moreover, the importance of lifestyle modification during hypertension treatment is often neglected by patients, therefore, there is an urgent need to educate hypertensive patients about the adherence to lifestyle modifications.
评估中国高血压患者样本中抗高血压治疗的依从性水平，并确定任何相关危险因素。在中国西安的一家三级医院对488名中国高血压患者进行了一项横断面研究。收集了有关社会人口学因素和高血压相关临床特征的数据。使用先前验证的工具：高血压患者治疗依从性量表来评估治疗依从性。共有27.46%的患者依从其抗高血压治疗。确定了三个与抗高血压治疗依从性独立相关的因素：性别（P = 0.034）、居住地（P = 0.029）、高血压病程（P < 0.001）。发现性别、居住地、职业以及使用抗高血压药物治疗的时长在某些类别中对治疗依从性有显著影响。中国高血压患者的治疗依从性较差。应设计更多关注和有效的策略来解决影响治疗依从性的因素。应加强对患者的高血压知识教育。此外，高血压治疗期间生活方式改变的重要性常常被患者忽视，因此，迫切需要对高血压患者进行关于坚持生活方式改变的教育。
