• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

老年全口义齿患者光动力疗法治疗口臭的疗效评估：一项随机对照试验方案

Evaluation of the treatment of halitosis with photodynamic therapy in older patients with complete denture: Protocol for a randomized, controlled trial.

作者信息

Vale Katia Llanos do, Horliana Anna Carolina Ratto Tempestini, Romero Sergio Dos Santos, Deana Alessandro de Melo, Gonçalves Marcela Leticia Leal, Ferrari Raquel Agnelli Mesquita, Bussadori Sandra Kalil, Fernandes Kristianne Porta Santos

机构信息

Postgraduate program in Biophotonics Applied to Health Sciences, Universidade Nove de Julho.

Postgraduate Program in Rehabilitation Sciences, Universidade Nove de Julho, UNINOVE, São Paulo, Brazil.

出版信息

Medicine (Baltimore). 2019 Jul;98(27):e16275. doi: 10.1097/MD.0000000000016275.

DOI:10.1097/MD.0000000000016275
PMID:31277154
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6635224/
Abstract

BACKGROUND

Halitosis is the term used to define an unpleasant odor emanating from the mouth. However, no studies have evaluated the causes and treatment of halitosis in the population of older adults with denture.

METHODS

A randomized, controlled trial is proposed. The patients will be divided into 2 groups: G1: older adults who wear complete dentures and will be treated with tongue scraper (n = 20); G2 older adults who wear complete dentures and will be treated with PDT (n = 20). If the halitosis persists, the participants will be submitted to hygiene procedures for the mucosa and dentures. The evaluation of halitosis will be made before and after treatments, with OralChroma. If the halitosis is solved, the participants will return after 1 week for an additional evaluation. Oral Health Impact Profile (OHIP-14) will be administered by a calibrated examiner on the day the patient history is taken (baseline) and 1 week after treatment for halitosis.

DISCUSSION

This protocol will determine the effectiveness of photodynamic therapy regarding the reduction of halitosis in older adults with complete denture.

TRIAL REGISTRATION

This protocol was registered in ClinicalTrial.gov, under number NCT03960983. It was first posted and last updated in May 23, 2019. https://clinicaltrials.gov/ct2/show/NCT03960983.

摘要

背景

口臭是用于定义从口腔散发出的难闻气味的术语。然而，尚无研究评估佩戴假牙的老年人群口臭的病因及治疗方法。

方法

拟进行一项随机对照试验。患者将被分为两组：G1组：佩戴全口假牙并将接受舌刷治疗的老年人（n = 20）；G2组：佩戴全口假牙并将接受光动力疗法（PDT）治疗的老年人（n = 20）。如果口臭持续存在，参与者将接受口腔黏膜和假牙的清洁程序。使用OralChroma在治疗前后对口臭进行评估。如果口臭得到解决，参与者将在1周后返回进行额外评估。口腔健康影响程度量表（OHIP - 14）将由经过校准的检查人员在采集患者病史当天（基线）以及治疗口臭1周后进行评估。

讨论

本方案将确定光动力疗法对减少佩戴全口假牙老年人口臭的有效性。

试验注册

本方案已在ClinicalTrial.gov上注册，编号为NCT03960983。首次发布及最后更新时间为2019年5月23日。https://clinicaltrials.gov/ct2/show/NCT03960983 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/7376fcee84eb/medi-98-e16275-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/013bdf0c0b78/medi-98-e16275-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/fd7d94e33c5d/medi-98-e16275-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/3241684854eb/medi-98-e16275-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/7376fcee84eb/medi-98-e16275-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/013bdf0c0b78/medi-98-e16275-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/fd7d94e33c5d/medi-98-e16275-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/3241684854eb/medi-98-e16275-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b74/6635224/7376fcee84eb/medi-98-e16275-g006.jpg

相似文献

1
Evaluation of the treatment of halitosis with photodynamic therapy in older patients with complete denture: Protocol for a randomized, controlled trial.老年全口义齿患者光动力疗法治疗口臭的疗效评估：一项随机对照试验方案
Medicine (Baltimore). 2019 Jul;98(27):e16275. doi: 10.1097/MD.0000000000016275.
2
Evaluation of halitosis in adult patients after treatment with photodynamic therapy associated with periodontal treatment: Protocol for a randomized, controlled, single-blinded trial with 3-month follow up.光动力疗法联合牙周治疗后成年患者口臭的评估：一项为期3个月随访的随机、对照、单盲试验方案
Medicine (Baltimore). 2019 Sep;98(39):e16976. doi: 10.1097/MD.0000000000016976.
3
Treatment of halitosis with photodynamic therapy in older adults with complete dentures: A randomized, controlled, clinical trial.全口义齿老年患者口臭的光动力疗法治疗：一项随机对照临床试验。
Photodiagnosis Photodyn Ther. 2021 Mar;33:102128. doi: 10.1016/j.pdpdt.2020.102128. Epub 2020 Dec 1.
4
Photodynamic therapy with Bixa orellana extract and LED for the reduction of halitosis: study protocol for a randomized, microbiological and clinical trial.使用红木提取物和发光二极管进行光动力疗法减轻口臭：一项随机、微生物学和临床试验的研究方案
Trials. 2018 Oct 29;19(1):590. doi: 10.1186/s13063-018-2913-z.
5
Oral hygiene associated with antimicrobial photodynamic therapy or lingual scraper in the reduction of halitosis after 90 days follow up: A randomized, controlled, single-blinded trial.口腔卫生联合抗菌光动力疗法或舌刮器治疗在 90 天随访后减少口臭：一项随机、对照、单盲试验。
Photodiagnosis Photodyn Ther. 2021 Mar;33:102057. doi: 10.1016/j.pdpdt.2020.102057. Epub 2020 Nov 22.
6
Antimicrobial capacity of photodynamic therapy on oral health-related quality of life and halitosis among elderly patients wearing removal dentures.光动力疗法对佩戴可摘义齿老年患者口腔健康相关生活质量及口臭的抗菌能力
Photodiagnosis Photodyn Ther. 2020 Dec;32:102059. doi: 10.1016/j.pdpdt.2020.102059. Epub 2020 Oct 13.
7
Photodynamic therapy as a novel treatment for halitosis in adolescents: study protocol for a randomized controlled trial.光动力疗法作为青少年口臭的一种新治疗方法：一项随机对照试验的研究方案
Trials. 2014 Nov 14;15:443. doi: 10.1186/1745-6215-15-443.
8
Comparative study between photodynamic therapy and the use of probiotics in the reduction of halitosis in mouth breathing children: Study protocol for a randomized controlled clinical trial.光动力疗法与益生菌在减少口呼吸儿童口臭中的应用比较：一项随机对照临床试验的研究方案。
Medicine (Baltimore). 2023 Apr 14;102(15):e33512. doi: 10.1097/MD.0000000000033512.
9
Action of antimicrobial photodynamic therapy with red leds in microorganisms related to halitose: Controlled and randomized clinical trial.红色发光二极管抗菌光动力疗法对与口臭相关微生物的作用：对照随机临床试验。
Medicine (Baltimore). 2019 Jan;98(1):e13939. doi: 10.1097/MD.0000000000013939.
10
Efficacy of antimicrobial photodynamic therapy against halitosis in adolescent patients undergoing orthodontic treatment.抗微生物光动力疗法治疗正畸青少年患者口臭的疗效。
Photodiagnosis Photodyn Ther. 2020 Dec;32:102019. doi: 10.1016/j.pdpdt.2020.102019. Epub 2020 Sep 17.

引用本文的文献

1
Effectiveness of lasers and aPDT in elimination of intraoral halitosis: a systematic review based on clinical trials.激光和 aPDT 治疗口腔口臭的疗效：基于临床试验的系统评价。
Lasers Med Sci. 2022 Dec;37(9):3403-3411. doi: 10.1007/s10103-022-03656-3. Epub 2022 Nov 24.
2
Effect of Photodynamic Therapy on Halitosis: A Systematic Review of Randomized Controlled Trials.光动力疗法治疗口臭的效果：一项随机对照试验的系统评价。
Sensors (Basel). 2022 Jan 8;22(2):469. doi: 10.3390/s22020469.

本文引用的文献

1
A Current Approach to Halitosis and Oral Malodor- A Mini Review.口臭与口腔异味的当前研究方法——一篇综述短文
Open Dent J. 2018 Apr 30;12:322-330. doi: 10.2174/1874210601812010322. eCollection 2018.
2
The application of antimicrobial photodynamic therapy (aPDT) in dentistry: a critical review.抗菌光动力疗法（aPDT）在牙科中的应用：一项批判性综述。
Laser Phys. 2016 Dec;26(12). doi: 10.1088/1054-660X/26/12/123001. Epub 2016 Nov 9.
3
Effect of photodynamic therapy in the reduction of halitosis in patients with multiple sclerosis: clinical trial.
光动力疗法对减轻多发性硬化症患者口臭的效果：临床试验
J Breath Res. 2017 Oct 27;11(4):046006. doi: 10.1088/1752-7163/aa8209.
4
Estimated prevalence of halitosis: a systematic review and meta-regression analysis.口臭患病率的估计：系统评价和荟萃回归分析。
Clin Oral Investig. 2018 Jan;22(1):47-55. doi: 10.1007/s00784-017-2164-5. Epub 2017 Jul 4.
5
Effect of antimicrobial photodynamic therapy 
and laser alone as adjunct to mechanical debridement in the management of halitosis: A systematic review.抗菌光动力疗法及单纯激光作为机械清创辅助手段在口臭治疗中的效果：一项系统评价。
Quintessence Int. 2017;48(7):575-583. doi: 10.3290/j.qi.a38264.
6
Prevalence of halitosis in elderly living in nursing homes.养老院老年人口臭的患病率。
Int J Dent Hyg. 2016 Nov;14(4):295-300. doi: 10.1111/idh.12236. Epub 2016 Aug 1.
7
Effect of photodynamic therapy for the treatment of halitosis in adolescents - a controlled, microbiological, clinical trial.光动力疗法治疗青少年口臭的效果——一项对照、微生物学、临床试验
J Biophotonics. 2016 Dec;9(11-12):1337-1343. doi: 10.1002/jbio.201600067. Epub 2016 Jun 1.
8
Halitosis: Current concepts on etiology, diagnosis and management.口臭：关于病因、诊断和治疗的当前概念
Eur J Dent. 2016 Apr-Jun;10(2):292-300. doi: 10.4103/1305-7456.178294.
9
User perception on various designs of tongue scrapers: an observational survey.用户对各种舌刮板设计的感知：一项观察性调查。
Int J Dent Hyg. 2017 Nov;15(4):e1-e8. doi: 10.1111/idh.12204. Epub 2016 Feb 10.
10
Halitosis: a review of the etiologic factors and association with systemic conditions and its management.口臭：病因及与全身状况的关联综述及其管理
J Contemp Dent Pract. 2014 Nov 1;15(6):806-11. doi: 10.5005/jp-journals-10024-1622.