Kellesarian Sergio Varela, Malignaggi Vanessa Ros, Al-Kheraif Abdulaziz A, Al-Askar Mansour, Yunker Michael, Javed Fawad
Quintessence Int. 2017;48(7):575-583. doi: 10.3290/j.qi.a38264.
The aim of the present study was to assess the efficacy of laser therapy (LT) and antimicrobial photodynamic therapy (aPDT) as adjunct to mechanical debridement (MD) on the management of halitosis.
In order to address the focused question "Is MD with adjunct LT and/or aPDT more effective in the management of halitosis compared with MD alone?" an electronic search without time or language restrictions was conducted up to January 2017 in indexed databases using the combination of different key words including photochemotherapy, lasers, light, photodynamic therapy, halitosis, and bad breath. The exclusion criteria included qualitative and/or quantitative reviews, case reports, case series, commentaries, letters to the editor, interviews, and updates.
Six randomized control trials were included and processed for data extraction. Results from all studies reported that MD with adjunct LT or aPDT is more effective in reducing halitosis and/or volatile sulfur compounds concentration associated with oral conditions compared with MD alone. One study reported a significant reduction in bacterial colony forming units on the dorsum of the tongue among patients with coated tongue receiving MD with aPDT compared with MD alone.
The efficacy of aPDT and/or LT on halitosis management remains unclear. Further well-designed randomized clinical trials assessing the efficacy of mechanical debridement with LT or aPDT on the halitosis treatment are needed.
本研究旨在评估激光治疗(LT)和抗菌光动力疗法(aPDT)作为机械清创术(MD)辅助手段在口臭治疗中的疗效。
为解决核心问题“与单纯机械清创术相比,联合激光治疗和/或抗菌光动力疗法的机械清创术在口臭治疗中是否更有效?”,截至2017年1月,在索引数据库中进行了无时间或语言限制的电子检索,使用了包括光化学疗法、激光、光、光动力疗法、口臭和口气不佳等不同关键词的组合。排除标准包括定性和/或定量综述、病例报告、病例系列、评论、给编辑的信、访谈和更新。
纳入六项随机对照试验并进行数据提取。所有研究结果均表明,与单纯机械清创术相比,联合激光治疗或抗菌光动力疗法的机械清创术在减少与口腔疾病相关的口臭和/或挥发性硫化物浓度方面更有效。一项研究报告称,与单纯机械清创术相比,接受联合抗菌光动力疗法的机械清创术的舌苔患者舌背细菌菌落形成单位显著减少。
抗菌光动力疗法和/或激光治疗在口臭治疗中的疗效仍不明确。需要进一步设计良好的随机临床试验来评估激光治疗或抗菌光动力疗法辅助机械清创术在口臭治疗中的疗效。