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妊娠高血压疾病。

Hypertensive Disorders of Pregnancy.

机构信息

Division of Nephrology, Kidney CARE Program, University of Cincinnati, 231 Albert Sabin Way, MSB 6211, Cincinnati, OH 45267, USA.

Buffalo Medical Group, 2121 Main Street #305, Buffalo, NY 14214, USA.

出版信息

Cardiol Clin. 2019 Aug;37(3):345-354. doi: 10.1016/j.ccl.2019.04.008. Epub 2019 May 8.

DOI:10.1016/j.ccl.2019.04.008
PMID:31279428
Abstract

Hypertensive disorders of pregnancy are common and contribute inordinately to maternal and fetal morbidity and mortality. Although not completely understood, recent clinical trials have provided important insights into pathogenesis of preeclampsia. Preeclampsia is considered a systemic disease with generalized endothelial dysfunction and risk of future cardiovascular disease. This review revisits the definitions and classifications of hypertensive disorders of pregnancy; discusses updates on pathophysiology, prevention, and early prediction of preeclampsia; reviews current management guidelines; and discusses potential risks and benefits associated with treatment. Improvement in management and outcomes of women with hypertensive disorders of pregnancy seems in sight in the near future.

摘要

妊娠高血压疾病很常见，会极大地增加产妇和胎儿的发病率和死亡率。尽管尚未完全了解，但最近的临床试验为子痫前期的发病机制提供了重要的见解。子痫前期被认为是一种全身性疾病，存在广泛的内皮功能障碍和未来发生心血管疾病的风险。本文回顾了妊娠高血压疾病的定义和分类；讨论了子痫前期的病理生理学、预防和早期预测的最新进展；综述了目前的管理指南；并讨论了治疗相关的潜在风险和获益。在不久的将来，妊娠高血压疾病妇女的管理和结局似乎有望得到改善。

相似文献

1
Hypertensive Disorders of Pregnancy.妊娠高血压疾病。
Cardiol Clin. 2019 Aug;37(3):345-354. doi: 10.1016/j.ccl.2019.04.008. Epub 2019 May 8.
2
Short- and long-term strategies for the management of hypertensive disorders of pregnancy.妊娠期高血压疾病管理的短期和长期策略。
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Hypertensive disorders of pregnancy: overdiagnosis is appropriate.妊娠期高血压疾病：过度诊断是合理的。
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Control of hypertension in pregnancy.妊娠高血压的控制。
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Hypertensive Disorders in Pregnancy Current Practice Review.妊娠期高血压疾病：当前实践综述
Curr Hypertens Rev. 2017;13(2):80-88. doi: 10.2174/1573402113666170529110024.
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慢性肾脏病育龄女性的高血压知晓情况
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Extracellular Non-Coding RNAs in Cardiovascular Diseases.心血管疾病中的细胞外非编码RNA
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Association of gestational hypertension and preeclampsia with offspring adiposity: A systematic review and meta-analysis.妊娠高血压和子痫前期与后代肥胖的关系：系统评价和荟萃分析。
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