Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu, 501-1194, Japan.
Department of Tumor Pathology, Gifu University School of Medicine, Gifu, Japan.
Skeletal Radiol. 2020 Jan;49(1):129-135. doi: 10.1007/s00256-019-03269-y. Epub 2019 Jul 7.
This study assessed the CT and MRI findings of solitary nevus lipomatosus cutaneous superficialis (NLCS).
Eleven patients with histopathologically and clinically confirmed solitary NLCS who underwent CT and/or MRI were enrolled. Radiological and histopathological findings of elevated lesions located above the level of the surrounding normal skin surface and coexisting subcutaneous lipoma-like lesions were assessed retrospectively.
Elevated skin lesions were observed in all 11 patients; these lesions were pedunculated in 4 patients (36%) and broad-based in 7 (64%). The CT attenuation of elevated lesions was fat attenuation in 2 out of 7 patients (29%), slightly increased fat attenuation in 4 out of 7 (57%), and combined fat and soft-tissue attenuation in 1 out of 7 (14%). The MR signal intensity of elevated lesions on T1-weighted images was fat signal intensity in 2 out of 6 patients (33%), slightly decreased fat signal intensity in 3 out of 6 (50%), and combined fat signal intensity and hypointensity in 1 out of 6 (17%). Subcutaneous lipoma-like lesions with fat attenuation and/or fat signal intensity were observed in 6 out of 11 patients (55%). Histopathologically, various amounts of fatty tissue and collagenous fiber were observed within the elevated lesions in all 11 patients.
The CT and MRI features of solitary NLCS were the broad-based or pedunculated elevated lesions, including fatty components. Additionally, subcutaneous lipoma-like lesions were frequently observed.
本研究评估了单发脂肪性神经皮肤脂肪瘤(NLCS)的 CT 和 MRI 表现。
回顾性分析了 11 例经组织病理学和临床证实为单发 NLCS 并接受 CT 和/或 MRI 检查的患者。评估了位于正常皮肤表面上方的隆起病变和并存的皮下脂肪瘤样病变的影像学和组织病理学表现。
11 例患者均观察到隆起性皮肤病变;4 例(36%)呈蒂状,7 例(64%)为宽基底状。7 例患者中,2 例(29%)隆起性病变 CT 衰减值为脂肪衰减,4 例(57%)为轻度增高的脂肪衰减,1 例(14%)为脂肪和软组织混合衰减。6 例患者中,2 例(33%)T1 加权图像上隆起性病变的 MR 信号强度为脂肪信号强度,3 例(50%)为轻度降低的脂肪信号强度,1 例(17%)为脂肪信号强度和低信号强度混合。11 例患者中有 6 例(55%)观察到皮下脂肪瘤样病变,具有脂肪衰减和/或脂肪信号强度。组织病理学上,所有 11 例患者的隆起性病变内均观察到不同数量的脂肪组织和胶原纤维。
单发 NLCS 的 CT 和 MRI 特征为宽基底或带蒂的隆起性病变,包括脂肪成分。此外,常观察到皮下脂肪瘤样病变。