Suppr超能文献

新型非侵入性诊断方法

Novel Noninvasive Diagnostics.

作者信息

Wiley Claire, Wise Catherine F, Breen Matthew

机构信息

Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, CVM Research Building, 1060 William Moore Drive, Raleigh, NC 27607, USA.

Program in Environmental and Molecular Toxicology, Department of Biological Sciences, North Carolina State University, NC State College of Veterinary Medicine, CVM Research Building, 1060 William Moore Drive, Raleigh, NC 27606, USA; NC State College of Veterinary Medicine, North Carolina State University, CVM Research Building, 1060 William Moore Drive, Raleigh, NC 27607, USA.

出版信息

Vet Clin North Am Small Anim Pract. 2019 Sep;49(5):781-791. doi: 10.1016/j.cvsm.2019.05.002. Epub 2019 Jul 4.

Abstract

Molecular diagnostics have revolutionized human oncology to allow early detection, targeted therapy, monitoring throughout treatment, and evidence of recurrence. By identifying genetic signatures associated with cancers, liquid biopsy techniques have been developed to diagnose and monitor cancer in noninvasive or minimally invasive ways. These techniques offer new opportunities for improving cancer screening, diagnosis, and monitoring the impact of therapy on the patients over time. Liquid biopsy also drives drug development programs. Similar diagnostics hold promise for comparable results in the veterinary field. Several noninvasive/minimally invasive techniques have been described in veterinary medicine that could be referred to as liquid biopsy.

摘要

分子诊断学彻底改变了人类肿瘤学,实现了早期检测、靶向治疗、全程治疗监测以及复发证据的获取。通过识别与癌症相关的基因特征,已开发出液体活检技术,以非侵入性或微创方式诊断和监测癌症。这些技术为改善癌症筛查、诊断以及长期监测治疗对患者的影响提供了新机遇。液体活检还推动了药物研发项目。类似的诊断方法有望在兽医领域取得可比的成果。兽医学中已描述了几种非侵入性/微创技术,可称之为液体活检。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验