Childs J E, Glass G E, Korch G W, Arthur R R, Shah K V, Glasser D, Rossi C, Leduc J W
Department of Immunology and Infectious Diseases, Johns Hopkins University School of Hygiene and Public Health, Baltimore, MD 21205.
Am J Epidemiol. 1988 Apr;127(4):875-8. doi: 10.1093/oxfordjournals.aje.a114871.
Human sera obtained from two sources in Baltimore were tested for antibodies against a Hantavirus by a variety of techniques. Four persons out of 1,788 had hantaviral antibody as demonstrated by immunofluorescent assay, enzyme-linked immunosorbent assay, and neutralizing assay. Neutralizing antibody titrations against three test viruses indicated that infections were caused by a rat-associated virus. Medical histories of two subjects indicated life-long residence in Baltimore and an absence of foreign travel, implicating a local source of infection.
对从巴尔的摩两个来源获取的人体血清，采用多种技术检测了抗汉坦病毒抗体。在1788人中，有4人通过免疫荧光测定、酶联免疫吸附测定和中和测定显示有汉坦病毒抗体。针对三种测试病毒的中和抗体滴定表明，感染是由一种与大鼠相关的病毒引起的。两名受试者的病史表明他们长期居住在巴尔的摩且没有出国旅行，这意味着感染源在当地。
