Department of Obstetrics and Gynecology, Hadassah University Hospital, Jerusalem, Israel.
Department of Obstetrics and Gynecology, Hadassah University Hospital, Jerusalem, Israel.
Eur J Obstet Gynecol Reprod Biol. 2019 Sep;240:139-143. doi: 10.1016/j.ejogrb.2019.06.036. Epub 2019 Jun 30.
Pregnancy is characterized by marked alterations in the hypothalamic-pituitary-adrenal axis and in the function of the adrenal gland. Some of those alterations have clinical characteristics that are similar to those of adrenal gland disorders. While adrenal disorders are rare among pregnant women, they harbor the potential for significant morbidity if they remain unrecognized and untreated. As the majority of patients with adrenal disorders present with clinical features that are typical of normal pregnancy - diagnosis during pregnancy is not uncommonly delayed. A high index of suspicion must be practiced for these disorders as they might carry severe obstetrical negative outcomes. In this review we will survey the normal function of adrenal glands in pregnancy and the role of adrenal hormones in pregnancy. We will outline the adrenal disorders that commonly present during pregnancy and review the literature on treatment modalities.
妊娠期间，下丘脑-垂体-肾上腺轴和肾上腺功能发生明显改变。其中一些改变具有类似于肾上腺疾病的临床特征。尽管肾上腺疾病在孕妇中较为罕见，但如果未被识别和治疗，它们可能会导致严重的发病率。由于大多数肾上腺疾病患者的临床表现与正常妊娠相似，因此在妊娠期间的诊断通常会被延迟。由于这些疾病可能会导致严重的产科不良结局，因此必须对其保持高度怀疑。在这篇综述中，我们将调查妊娠期间肾上腺的正常功能以及肾上腺激素在妊娠中的作用。我们将概述常见于妊娠期间的肾上腺疾病，并回顾相关的治疗方法文献。
