Beth Israel Deaconess Medical Center Harvard Medical School, Department of Anesthesiology, Critical Care and Pain Medicine, Boston, MA, USA.
Department of Anesthesiology, Maimonides Medical Center, Brooklyn, NY, USA.
Curr Pain Headache Rep. 2019 Jul 8;23(8):55. doi: 10.1007/s11916-019-0792-y.
Chronic pain of the lower extremity remains challenging to manage. Radiofrequency ablation procedure applies heat to nerve fibers with the goal of mitigating chronic pain conditions of the knee. However, the clinical efficacy has not yet been adequately established. The goal of this review paper is to report the use of radiofrequency ablations in the treatment of osteoarthritis of the knee.
PubMed and the Cochrane Controlled Trials Register were searched (final search 28 February 2018) using the MeSH terms "radiofrequency ablation," "neurolysis," "radiofrequency therapy," "pain syndrome," "analgesia," and "pain" in the English literature. Bibliographies of the published papers were screened for relevance to lower extremity radiofrequency ablation therapies. The quality of selected publications was assessed using the Cochrane risk of bias instrument. Of the 923 papers screened, 317 were further investigated for relevance. Our final search methodology yielded 19 studies that investigated the use of radiofrequency ablation at the knee. Of these 19 studies, there were four randomized control trials, two non-randomized control trials, three prospective studies, two retrospective studies, one case-control study, one technical report, and seven case reports. In summary, the data available suggests radiofrequency ablation as a promising and efficacious with all 19 studies revealing significant short- and long-term pain reductions in patients with knee pain.
下肢慢性疼痛的治疗仍然具有挑战性。射频消融术通过加热神经纤维来减轻膝关节的慢性疼痛，但尚未充分确立其临床疗效。本文的目的是报告射频消融术在膝关节骨关节炎治疗中的应用。
在英文文献中，使用 MeSH 术语“射频消融”、“神经松解”、“射频治疗”、“疼痛综合征”、“镇痛”和“疼痛”，在 PubMed 和 Cochrane 对照试验登记处进行了检索（最终检索日期为 2018 年 2 月 28 日）。对已发表论文的参考文献进行了筛选，以确定与下肢射频消融治疗相关的内容。使用 Cochrane 偏倚风险工具评估选定出版物的质量。在筛选的 923 篇论文中，有 317 篇进一步进行了相关性研究。我们最终的搜索方法产生了 19 项研究，这些研究调查了膝关节射频消融的使用。在这 19 项研究中，有 4 项随机对照试验、2 项非随机对照试验、3 项前瞻性研究、2 项回顾性研究、1 项病例对照研究、1 项技术报告和 7 项病例报告。总之，现有数据表明射频消融术具有很大的应用前景和疗效，所有 19 项研究均表明，接受射频消融术的膝关节疼痛患者的短期和长期疼痛均有显著减轻。
