Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macau, China.
Guangdong-Macau Traditional Chinese Medicine Technology Industrial Park Development Co., Ltd., Zhuhai, China.
Crit Rev Food Sci Nutr. 2020;60(14):2342-2352. doi: 10.1080/10408398.2019.1635567. Epub 2019 Jul 9.
L. (fenugreek) is one of the oldest applied medicinal herbs. Significant pharmacological and clinical evidence have highlighted the medicinal application of fenugreek. Explore the current knowledge regarding the bioactivity (animal aspects) and clinical application of fenugreek and its bioactive components, as well as the products, markets and patents related to fenugreek. This review highlights the phytochemicals, bioactivity (animal aspects) and clinical application of fenugreek from recent literatures and products, markets and patents from database. Until now, more than 100 phytochemicals have been isolated from fenugreek seeds, mainly including polysaccharides, saponins, alkaloids, phenolic acids, and flavonoids. Fenugreek extract and its bioactive compounds showed excellent antidiabetic activity and anti-obesity activity in animal and human study. Although the fenugreek seed has been used as TCM raw materials for a long time of period in China, China is lacking the research of fenugreek in both depth and width.
L.（葫芦巴）是最古老的应用药用草本植物之一。大量的药理学和临床证据强调了葫芦巴的药用应用。探讨了葫芦巴及其生物活性成分的生物活性（动物方面）和临床应用，以及与葫芦巴相关的产品、市场和专利。本综述从最近的文献和数据库中的产品、市场和专利中突出了葫芦巴的植物化学物质、生物活性（动物方面）和临床应用。到目前为止，已经从葫芦巴种子中分离出 100 多种植物化学物质，主要包括多糖、皂苷、生物碱、酚酸和类黄酮。葫芦巴提取物及其生物活性化合物在动物和人体研究中表现出优异的降血糖活性和抗肥胖活性。尽管中国长期以来一直将葫芦巴种子用作中药原料，但中国在葫芦巴的研究深度和广度上都有所欠缺。
